ID A0A0D1ZQ53_9EURO Unreviewed; 354 AA.
AC A0A0D1ZQ53;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=2-dehydropantoate 2-reductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV08_07707 {ECO:0000313|EMBL:KIW14922.1};
OS Exophiala spinifera.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW14922.1, ECO:0000313|Proteomes:UP000053328};
RN [1] {ECO:0000313|EMBL:KIW14922.1, ECO:0000313|Proteomes:UP000053328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW14922.1,
RC ECO:0000313|Proteomes:UP000053328};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala spinifera CBS89968.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847496; KIW14922.1; -; Genomic_DNA.
DR RefSeq; XP_016235138.1; XM_016382036.1.
DR AlphaFoldDB; A0A0D1ZQ53; -.
DR STRING; 91928.A0A0D1ZQ53; -.
DR GeneID; 27334790; -.
DR VEuPathDB; FungiDB:PV08_07707; -.
DR HOGENOM; CLU_031468_2_1_1; -.
DR OrthoDB; 1816688at2759; -.
DR Proteomes; UP000053328; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF30; 2-REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00740)-RELATED; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053328}.
FT DOMAIN 7..165
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 203..330
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 354 AA; 38820 MW; 05F0AC6EC109230D CRC64;
MAEKVRVLLV GSGGIGTMTA LNLELGGHAA VSAVLRSNYA AVKEKGFTID SCDHGKFEGW
RPSEILSKVP DVVSDPSAKP FDYIICTTKN IPDVPPVLVD IIRPAVTPGK SVILLIQNGL
NIEKPLLKEF PTNILLSGVS FMGADELSPG HVLENDTDRL SVGPFFNPAL EIGDQIAAAE
HFVKIYSATG KVQCSYDRDV LFIRWRKLLY NAVWNPICAI TGMDTTRLRL ASEDDDPGSP
LNTLVRPAMN EIRAAASAVA GVSLPESLVE VMVDADPLEI WCAPSMMQDT RKKRFIEYEY
LVGEALRAGE SKGVAMPTLR CIYGFCKAVQ WRTKEHHGLV DPQKLMEERK KARV
//
