ID A0A0D2A0J3_9PEZI Unreviewed; 1036 AA.
AC A0A0D2A0J3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=PV09_08338 {ECO:0000313|EMBL:KIW00163.1};
OS Verruconis gallopava.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Sympoventuriaceae; Verruconis.
OX NCBI_TaxID=253628 {ECO:0000313|EMBL:KIW00163.1, ECO:0000313|Proteomes:UP000053259};
RN [1] {ECO:0000313|EMBL:KIW00163.1, ECO:0000313|Proteomes:UP000053259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 43764 {ECO:0000313|EMBL:KIW00163.1,
RC ECO:0000313|Proteomes:UP000053259};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Ochroconis gallopava CBS43764.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
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DR EMBL; KN847567; KIW00163.1; -; Genomic_DNA.
DR RefSeq; XP_016210032.1; XM_016362215.1.
DR AlphaFoldDB; A0A0D2A0J3; -.
DR STRING; 253628.A0A0D2A0J3; -.
DR GeneID; 27316311; -.
DR VEuPathDB; FungiDB:PV09_08338; -.
DR HOGENOM; CLU_004414_0_1_1; -.
DR InParanoid; A0A0D2A0J3; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000053259; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000053259};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 107..255
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 345..1032
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
FT REGION 619..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 116122 MW; 841153C1B834EA1E CRC64;
MDIAQVENAI NIAWDHTSPP DIKQQALAFI HQLRTDPASW QVCLPLFVQD RQPPDNTRHF
LLDALNNSIK SEQVENQARL YIKETLWMYV RKKYGTGSPD DTADSLVIRN KLTQTLTFLF
TTLYASGWES FVDDFLDLAG NGSLGRTNIS GTALYLRTLE SIHDEIADVM IPRTPEEAKR
NADLKDLIRA RDAQKVSQSW QEILANWRSL DLNIVQMCLR VLARWVSWVD ISLVVNETVL
QPLLDMAGQQ GLKDHSSLEV KVRDAAIDAI SETAGKKMVP PAKVQLLEFL NLSTVVGQLI
ASPPLAELKG TPDYDVDLAE AVAKLVNNVM RDTISVLDTS GVDDQTLQKA DALLQIFVPY
LLRFFSDEYD EVCSTAMESM TELLGYFRKL GKKEALPQRY ATMLPAILNA IIKKMEYDET
ASWGEEEDQT DEAEFLELRK RLHVLQQNVA AIDEQLYMDT LTNLVANTLN KLGAGSNEIN
WRELDLALYE MYLFGDLASK NKGLYAKREP SSVAAVRLVE MMTRMMESNV DTYNHPAIQL
QYMELCARYI QFFENSQSFI PKALDVFVRY AHHPREKVRA KSWYLFLRFV RGLRGHLGEV
SQTIIQAIGD LLTIKATLPV DRDDDSEDED DDSEVDPGRD PHFDNQCNLF EAIGCISSNS
SLPMETRLLY VQSVMNPIFA DMEQTLPAVK SGDERAQMQL HHDIKALGTL VRGYTDWMPG
VKTSTPPPPE VSAEFLRAAE AILIALESLS SSQLIREASR FAFARLIGGC GVSLFPQLPR
WVDGLLTNSS SKIETVFFLA QLKQVMFVFK AEMFGVLDVI LSPLLQRIFT RLGESPEGTD
DEIQLNDLRK EYINVIGVIL NNDLAGVLVS TRNQGYFESV IATIEHFARD PSDLALARTA
FGVLTKMVSV WGGPDTAIQV NPNSETPASP TSIPPQPVLP GFDQFIITRF SPLSWSIPAT
PGFKVQDPVS RQLVAEIAQL QQEILKKTGA LYLASIEQEL RGMGAADADV NLYLEKLRAD
PKSFKDFLIG FLGRGR
//
