ID A0A0D2A221_EXOME Unreviewed; 1637 AA.
AC A0A0D2A221;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=PV10_04313 {ECO:0000313|EMBL:KIV93068.1};
OS Exophiala mesophila (Black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=212818 {ECO:0000313|EMBL:KIV93068.1, ECO:0000313|Proteomes:UP000054302};
RN [1] {ECO:0000313|EMBL:KIV93068.1, ECO:0000313|Proteomes:UP000054302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 40295 {ECO:0000313|EMBL:KIV93068.1,
RC ECO:0000313|Proteomes:UP000054302};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala mesophila CBS40295.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KN847522; KIV93068.1; -; Genomic_DNA.
DR RefSeq; XP_016224642.1; XM_016368854.1.
DR STRING; 212818.A0A0D2A221; -.
DR GeneID; 27322158; -.
DR VEuPathDB; FungiDB:PV10_04313; -.
DR HOGENOM; CLU_001640_2_0_1; -.
DR OMA; WKNWIVL; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000054302; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054302};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..876
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1027..1048
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1069..1091
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1103..1123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1130..1152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1172..1196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1217..1234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..698
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1276..1503
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 768..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1637 AA; 179746 MW; 4D65143C91BECD7B CRC64;
MILFFRQVWS LTLKNLLIFF IRHSFSTTLR AFILPCIYVG FLSYARYLFI SPSVFGIGEP
TPVRALSSAL DLASGGRDRL VFVNNGFSGG QIESVINQVV DQTSGFGGHV EVFSEEEELL
TRCRNSIRGT SRCIAAAVFF SSPTEGPGDL WNYTIRADGG LANKIVTDSD DNDAEIYLFP
LQHAIDRAIA EEENGSDDAT SIPELVDEYP YTSMTKEQRQ ARIRTRYQGG IIDILAVAFF
IQMVGVTYQL TGIIATEREI GMAQLLDCMM PNAKRWQPQM ARIMANHLAF DMLYGPGWIV
IGIILSLGVF TNTSAAIIII YHILSGLSLA SFSIFGAAFF KKAQLSGITS VIVSLLLGII
AQVAAKAGTA SVAILSLLFP PMNYVYFIIF IARWERQDRP ANLVQSAPEN PSTLPGIALW
IFTIIQILVF PVLGAFIERR LYGTASKSRK TNYSDSQTAI SLDGFTKEYP PTHAARFLSF
FTRRSAKSVL AVDHLTLQAA RGQIMVLLGA NGSGKSTTLD AIAGLHSITS GEISINYPES
KTGLGLCPQK NVLWDDLTVE EHVRIFNRIK SQVPATKQEN TTLLELCDIS KKSTARSKTL
SGGQKRKLQL AMMFTGGSRV CCVDEVSSGL DPLSRRKIWD ILLAERGARS IILTTHFLDE
AELLADHIAI LSKGVLKASG TSVELKHKLG SGYRVHVYNT HGKLNIPKYD DVNHVSHDDQ
TIYNLADSAT TANFLRRIDE HGVSEYQVSG PTIEDVFLKV AEEVSTANTV PEKPIPGQEA
STSSTPEKMM QIQETGSRSS AEAPDAPGGE MASDAFYGSV KPAEVPQLLD GHRIGMTKQA
WVLFSKRMVV LRRNYFPFLA ALLIPIVAAG LVTLFLNDFQ LAGCTPEETV GISDVESLTS
QEDFLLVAGP SDRLSIEAVS RLGDTLSGTI GSSLSGSQLL DSVHVVDSLQ EFNDYIQNNF
ANVTPGGFFL GDGDSPPTFA WRGNGNVAFG TIVQNLMDTL LSNISIASQY QAFDMPWPQD
IGKALQLITY FGLAMSVYPS FFALYPTIER LRNVRGLHYS NGVRSAPLWL AYTSFDFIIV
LLASAIATVI FRAVTDVWYH IEYLFVVFFL YGLASTLLSY VISLFARSQL AAFAFAAGGQ
AVMFLLYFIA YMSVLTYSPI DQIDANVNIC HFAIATISPV ANLTRALFVS LNVFSITCRD
RDFASYAGSM TTYGGPILYL ILQSFFLFGL LLWWDSGPLL NKLRRKQKEE EIEDQDTVEA
EVSNELTRVV SSHDGLRVVN LTRRFKKNIA VNNVTFGVPK SEVFALLGPN GAGKSTTISL
IRGDIQPSHR GGDILVDGIS VIRHRAQARS RLGVCPQFDA MDTMTVVEHL YFYARVRGVT
KPAVNVEAVM RAVGLEQYGD RMAAKLSGGN KRKLSLGIAL MGNPSVLLLD EPSSGMDAAS
KRVMWRTLAS VVPGRSLVLT THSMEEADAL ATRAGIMAGK MLALGTTDYL RNKHGDSYYV
HLVHRHAPHA SEQEMQRIRD WIEYNLPEAE IESKIYAGQI RFSVPSSTAR KDKEAGTESN
SGIAQLFTSL EKNKEDLQIE YYSVSRATLD QVFLNIVGKH NVEEEGAASE AVRSSKQKRG
GGFAKIGKWL KLGKSVS
//
