ID   A0A0D2A430_EXOME        Unreviewed;      1184 AA.
AC   A0A0D2A430;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=DNA damage-binding protein 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV10_04949 {ECO:0000313|EMBL:KIV93758.1};
OS   Exophiala mesophila (Black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=212818 {ECO:0000313|EMBL:KIV93758.1, ECO:0000313|Proteomes:UP000054302};
RN   [1] {ECO:0000313|EMBL:KIV93758.1, ECO:0000313|Proteomes:UP000054302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 40295 {ECO:0000313|EMBL:KIV93758.1,
RC   ECO:0000313|Proteomes:UP000054302};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala mesophila CBS40295.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DDB1 family.
CC       {ECO:0000256|ARBA:ARBA00007453}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KN847522; KIV93758.1; -; Genomic_DNA.
DR   RefSeq; XP_016225332.1; XM_016369544.1.
DR   AlphaFoldDB; A0A0D2A430; -.
DR   STRING; 212818.A0A0D2A430; -.
DR   GeneID; 27322794; -.
DR   VEuPathDB; FungiDB:PV10_04949; -.
DR   HOGENOM; CLU_002893_1_1_1; -.
DR   OMA; HQDFLMR; -.
DR   OrthoDB; 226997at2759; -.
DR   Proteomes; UP000054302; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.10.150.910; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR10644:SF3; DNA DAMAGE-BINDING PROTEIN 1; 1.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054302}.
FT   DOMAIN          73..572
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          785..1142
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
FT   REGION          1035..1059
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1037..1058
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1184 AA;  129731 MW;  F4EC3109C601C45D CRC64;
     MSYVVPIHHA SGVRHAIKLN FLEPGIDTLV VAKANRLLIY EQGPEGLNLL YTKTVYGYIT
     ILESIRPSSS RTDHLFVGTD RYQYFTCSWN PNLKQLHTEQ SYVDLADKVL RDSRENDRCH
     IDPTRRFMTL ELYDGVVSIL PFIQPSNKRQ ARDHSSASPV GSLGEPVQVR IEELLTRSSA
     FMDAEPGSKD KPQLAILWED NSENPQLKLR QLTYLPTGDQ PTAELETVAE LSGDQLDQGV
     SHLIPVSAPY YGFLILGDHA IRYVDRDLSH VVTQDLADEA TIWTCWTKID DTRWLLADDY
     GKLFFLMIEV GDLDVLGWRL DPVGVASKAS TLVYLDDGYV FVGSHSGDSQ VVHIEEEGIR
     IVQTLDNIAP ILDFTIMDLG RGADSGKPSE FSSGQARIVA ASGAWQDGSI RSVRSGVGLE
     LLGTIGELSH ITDLWALSST GRGRTHDILV ASFVNETRVF AFDSEATVEE LDDFHHLDLS
     QPTLLAANFS DRKLAQVVES GVRITDLDSG MQTLDWRPTD ASSKLTAAAS NSVHLLVVQG
     GHTLHVFHTA HSDSKPSVSK TFPSDSQISG VAIPESSSNI CVVLFWQSSS VAILDLHSLE
     PTCLQTLGTP GTDIPRSVLV ANVLPDAPPS LFIAMADGTV LTYSLDLANN SLSNMSRVIL
     GTEPVFFKEL PRGQGPDSNL SHVFASCEQP SLIYSSEGRI VFSAVNAESA SRVCYFNTEA
     YPDAVAVATP SELQLASIGT KTATQLQTLP IRETVRCLTY EPDAKIFAMG CIRRIMESGV
     EELLSSVKIA DEVSFKTLDS IELKDGELVQ CIVSVGSLDD AESPQGPYFV VGTSYLAKDD
     NGEEVSKGRI IIYEVNREKK LKIVTELLVK GVVSSLAMCE GKLVAGLLKT VVLYGLRSSS
     TRGRSSLELV RLATYRTASN PLSLAVTPST EDTPALIAVA DIMRSVSVLK VVLPDEEDAN
     YYLREISRHF ATVWCSAIAA TVEHEWIVGD MEGNLLALRQ NRDAPVDEAW RRMEVIGEFR
     LGEVVNKIVP ISRVPGPSQV SDESSGNGNE SSKGKNKLSI AAPRTGPLVT PRAFIATVEG
     AIYMLATINP AFVNVLLLLQ TALATRVQAP GFMPWSKYRA WQTTVVEKDE PFRFVDGEML
     EQGLLSLSDA DLEQVLEEAG LRDARHNVTV DEIKAWGESL RRLY
//