ID A0A0D2ABK4_9EURO Unreviewed; 1125 AA.
AC A0A0D2ABK4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV07_12463 {ECO:0000313|EMBL:KIW22142.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW22142.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW22142.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW22142.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
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DR EMBL; KN847048; KIW22142.1; -; Genomic_DNA.
DR RefSeq; XP_016242358.1; XM_016399990.1.
DR AlphaFoldDB; A0A0D2ABK4; -.
DR STRING; 569365.A0A0D2ABK4; -.
DR GeneID; 27351657; -.
DR VEuPathDB; FungiDB:PV07_12463; -.
DR HOGENOM; CLU_003612_1_1_1; -.
DR OrthoDB; 129892at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
DR Pfam; PF05833; NFACT_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
FT DOMAIN 553..666
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 978..1085
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 269..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1095..1125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..464
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..760
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..949
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1125 AA; 123528 MW; 3E5BFA87CA4C2BDA CRC64;
MKQRFSSLDV KVIANELSTS LTGLRLSNVY DLSSRIFLFK FAKPGRREQL LLDSGFRCHL
TSFSRTAATQ PSAFVSRLRH YLKSKRVTGI SQVGTDRVIE ISFSDGLYRL FLEFFAAGNI
IVTDADLNVL ALQRQVNEGD ADVDVKLGGK YKLEPKQNFH GVPPISEERV REVLQKAVER
SKAAKEVGGK KAKRAKGVDD LGKALSAGFP EFPQHLLEHA FRETGVDPTL KADDVLGDSK
SLRTVMTALQ TADEIFKSLG TGQSKGYIIA KQKSPPPGET EPSGAQETTR ESVLYDDFHP
FRPIQFQNKP GVHILEFDGF NRTVDEFYSS IESQKLESRL TEREEIAKRK LQVAKDEHEK
RLAGLQQVQE LHVRKAQAIE ANIHRVEEAC AAVNGLIAQG MDWIDIGKLI ENEQKRGNVV
AQMVKLPLKL EENTVTLLLD EPSFDEGYES DEEDETDDEA ESDEEDQGTR GKGGSSTDKR
LAIDIDLALS PWANARLYHD QKKSAAVKEK KTVEASSKAL KSAEQKIEAD LKKGLKQEKA
VLRPARKQFW FEKFLYFISS DGYLVIGGKD AQQNELLYRR YLKKGDVYVH ADLQGASSVI
VKNNPRTPDA PIPPSTLSQA GTLTVCTSSA WDSKALMGAW WVNADQVSKT APTGEYLTAG
GFVIRGRKIQ LTPSQLLLGF GVLWLISEES RVNHGKHRLD RTESMLPGEA EALANDVRGF
STGKQDVSEE VGPDQGQAVP DVEDAADAAV EEEEDDDHGA ALNEVPELPG NVDGDADDRD
STDTSEAEEE RSNPLQANLA QSCQDTKDDD DEEDKLSVGI EDETKEQHSD EASQGEESDD
TPATQPSTRA STPASASQAM AKSKPAQLAR GKRTKLKRAQ KKYADQDEED RALAMQLLGS
NRSQERKEAA EAEKAVREAK AQADKERRRA QHSKAAERER LRRDRLEKAA ASGANGGEGA
DLDEDDELSK EQLEQERREL LDIDRLVPMP EPGDELLAAI PVVAPWTALA RQKYKIKLQP
GNVKKGKVVR EILGFWTSLA TRGPKVVDEQ NREKEKVWRR EMDLLKEWRL EEIVGALPVK
GCRIVQSGGL GGALGGGSAG GGGGGGGKGG GGKGKGKAGG GKKGR
//
