ID A0A0D2AH07_9EURO Unreviewed; 849 AA.
AC A0A0D2AH07;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=PV06_09161 {ECO:0000313|EMBL:KIW39386.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW39386.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW39386.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW39386.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; KN847340; KIW39386.1; -; Genomic_DNA.
DR RefSeq; XP_016259602.1; XM_016410580.1.
DR AlphaFoldDB; A0A0D2AH07; -.
DR STRING; 215243.A0A0D2AH07; -.
DR GeneID; 27361235; -.
DR VEuPathDB; FungiDB:PV06_09161; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 91..736
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT REGION 430..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 397
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 849 AA; 94323 MW; 73344D4A907C11EB CRC64;
MINLLTMPIS IAGTRYFSQP ASIGDTLSRA SPKAEVDGMA AEHVERALEA AKDVKESYSK
QEKEPMSAQT LPKEHTKRGI TFAAQNKLPK LPIPDLDATM KRYLEALAPL QTIQEHNETR
ASVRDFLDHE GKDLQDRLKK YATDKTSYIE QFWYDSYLNY DNPVVLNLNP FFLLEDDPTP
ARNNQVTRAA SLVISALCFV RAVRKEELPP DTLRGTPLDM YQYSRLFGTA RVPTESGCII
GQDSDSKHVV VMCRGQFYWF DVLDDNHDII MTEKDLAINL QVIVNDAEEI PIQEAARGAL
GVLSTENRKV WSGLRDLLTR DEGSNNADCL SIVDSALFMI CLDYTEPADV SQLCGNMLCG
TNEVVRGVQV GTCTNRWYDK LQIIVCKNGS AGINFEHTGV DGHTVLRFAS DVYTDTILRY
AKSINGQAPT LWTSQSPDPS KRDPDSFGDV KTTPHKLEWD MTPELSIALR FAETRLADLI
NQNEFQTLDF SGYGKNFITS MGFSPDAFVQ MAFQAAYYGL YGRVENTYEP AMTKMFYHGR
TEAIRSVTPE SVDFVKTFWA DNTPQKKIEA LKSACQKHTA VTKEASKAQG QDRHLYALYC
VWQRKMNEEG AELASNADFS SNGYSSPTDP SDAGSPKRLD ERPISPTRSH AGTESSRSPG
PALHQMPPLF SDAGWEKINN TILSTSNCGN PSLRHFGFGP VSGDGFGIGY IIKEDSISVC
ASSKHRQTRR FVDSLESYLN EIRRLLKATR PRATSGGKLT RAREAEEVGK DGRLKSRGRA
IKAEATRADG TQTPTSMDTA EVEDDGLGGY GFFDAGMLLQ ALKKDAPKPA EQLAQKKRTV
GKKLALTEY
//
