ID   A0A0D2ALD1_9EURO        Unreviewed;      1134 AA.
AC   A0A0D2ALD1;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   13-SEP-2023, entry version 32.
DE   RecName: Full=Mitochondrial presequence protease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV07_08983 {ECO:0000313|EMBL:KIW25842.1};
OS   Cladophialophora immunda.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW25842.1, ECO:0000313|Proteomes:UP000054466};
RN   [1] {ECO:0000313|EMBL:KIW25842.1, ECO:0000313|Proteomes:UP000054466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW25842.1,
RC   ECO:0000313|Proteomes:UP000054466};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN847044; KIW25842.1; -; Genomic_DNA.
DR   RefSeq; XP_016246058.1; XM_016396202.1.
DR   AlphaFoldDB; A0A0D2ALD1; -.
DR   STRING; 569365.A0A0D2ALD1; -.
DR   GeneID; 27348177; -.
DR   VEuPathDB; FungiDB:PV07_08983; -.
DR   OrthoDB; 227593at2759; -.
DR   Proteomes; UP000054466; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43016:SF16; METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED; 1.
DR   PANTHER; PTHR43016; PRESEQUENCE PROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..1134
FT                   /note="Mitochondrial presequence protease"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002248918"
FT   DOMAIN          124..207
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          264..441
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   REGION          1082..1134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1085..1115
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1134 AA;  127596 MW;  A37C6B9B85D41B62 CRC64;
     MHAKLAILLT SLLVCFLATL FSSTLDHVFS QLINGKDQPA NLKWGVQQQI SQLLDQALTK
     IPSFASMVSI RAKPRFRQRQ RIDPDYCPCT ITQYESERTG MRVVVVDQEG PKLHGFFVLA
     TEIHDDSGAP HTLEHLCFMG SKSYKYKGFL DKLATRAYAG TNAWTATDHT AYTLETAGWA
     GFAQILPVYL EHVILPTLTD AGCTTEVHHV DGSGNDAGVV YSEMQGVQNM ASELIELQSK
     KILYPEGVGY RYETGGMLEQ LRVLTADRIR EFHREMYQPK NLCVAIFGEA NHDELLAILD
     EFETSILPDI PSPDAPFKRP WIESKLAPAL NQTTLLRVEF PEEDESFGEV DIRFLGPNCA
     DALELGALNV ALNYLAGSSA AVLDHVLVEK EQLASSVYYQ LDSRPRTEIQ FSLSSVETKR
     LEEVEKRFFE VLKEAMEQPL NMDFMKDCID RVVRTTKYNA EGSATAFADF IISDYLYGKR
     DGSTLEIVKS LKHYTQALAS WTEDQWKAYI KKYISDAPHV SILGVPSARL SEKLKTDEAN
     RIEEQKARLG PEGLKRMQEK LDAAKAENDR EIPRDLLGKF KVPLTDSIHF VTIPGARAGR
     ALDLGRRDNR FQKIIDEDAK DVPLFINFEH IPTNFTRVHL IISTETLPDD LRPLLAIYME
     AFWSLPIKRG DEIIDFRQVV TELERDTVGY SIDAANNLGN VEGIRISFQV ERERYGVAVK
     WLTELLYNSI FDVERLRAVN TRLLADVPDA KRSGDDMMMT VHFMTHLAPK SITRARTILV
     KALYLKRIRH LLKVDPERVV SQLERLRNLL CRFENYRILV ITDLEKTQKP VSTWQPFLEK
     LEPTKELNPI GRRIDRLSDA GKNPGKLAYV VPMPTIDSSF AFAVARGPTS YDDPQLPAIM
     VALAYMNAVE GPLWVAVRGT GLAYGTNMGF DIESGFIHID VYRSPDAYKA FEASRKIISD
     YMTGAVDFDP LMLEGAISSI VVMFANEQAT LAGAAAMSFI RSIMQRLPDD HMQRMLKRVR
     EVSVQDIKDA LEKVVFNVFV PEKADIVVTC APGLKEGIAG GLKDAGFSPE IRDLNYFQDD
     YGLKPIDGED EEDDDDDDDE EEDGDEDEDG REDTEGSDDI GGSEGYEIIE GNED
//