ID A0A0D2APH5_9PEZI Unreviewed; 310 AA.
AC A0A0D2APH5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Methylisocitrate lyase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV09_07540 {ECO:0000313|EMBL:KIW01024.1};
OS Verruconis gallopava.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Sympoventuriaceae; Verruconis.
OX NCBI_TaxID=253628 {ECO:0000313|EMBL:KIW01024.1, ECO:0000313|Proteomes:UP000053259};
RN [1] {ECO:0000313|EMBL:KIW01024.1, ECO:0000313|Proteomes:UP000053259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 43764 {ECO:0000313|EMBL:KIW01024.1,
RC ECO:0000313|Proteomes:UP000053259};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Ochroconis gallopava CBS43764.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate +
CC succinate; Xref=Rhea:RHEA:16809, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:30031, ChEBI:CHEBI:57429; EC=4.1.3.30;
CC Evidence={ECO:0000256|ARBA:ARBA00001050};
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DR EMBL; KN847558; KIW01024.1; -; Genomic_DNA.
DR RefSeq; XP_016210893.1; XM_016361318.1.
DR AlphaFoldDB; A0A0D2APH5; -.
DR STRING; 253628.A0A0D2APH5; -.
DR GeneID; 27315513; -.
DR VEuPathDB; FungiDB:PV09_07540; -.
DR HOGENOM; CLU_027389_3_0_1; -.
DR InParanoid; A0A0D2APH5; -.
DR OrthoDB; 554215at2759; -.
DR Proteomes; UP000053259; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00377; ICL_PEPM; 1.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR039556; ICL/PEPM.
DR InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR42905; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR42905:SF2; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR Pfam; PF13714; PEP_mutase; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000053259}.
SQ SEQUENCE 310 AA; 33044 MW; 49A6A2C1B95AF282 CRC64;
MTANGTNGVH TPMSAATKLR RMIEDPNGFV AAPGVHDGLS ARTVLEQGGF DCLYMTGAGT
TASRLGTADL GIATINDMRA HAEMIANLDP SIPLIADMDT GYGGPVMVAR SVEAYARSGV
AGFHIEDQVQ QKRCGHLLGK QLVDEETYVS RIRAAVAARK RIGSDIVIIA RTDALQSLGY
DAAIQRLKAA RDAGADVAFL EGMTDKEMCR RAVKDLAPWP SLLNMVEYGV TPIISADEAK
EMGFKVIIWP FATVVPAYVA MRDAIKGLKK TGVQNTPEGI GPRKIFEVCG LEGYMAFDAE
TGGTMYAKGA
//
