ID A0A0D2AT08_9EURO Unreviewed; 1226 AA.
AC A0A0D2AT08;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=PV07_07978 {ECO:0000313|EMBL:KIW28302.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW28302.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW28302.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW28302.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; KN847043; KIW28302.1; -; Genomic_DNA.
DR RefSeq; XP_016248518.1; XM_016395099.1.
DR AlphaFoldDB; A0A0D2AT08; -.
DR STRING; 569365.A0A0D2AT08; -.
DR GeneID; 27347172; -.
DR VEuPathDB; FungiDB:PV07_07978; -.
DR HOGENOM; CLU_001867_1_0_1; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 2.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
FT DOMAIN 87..249
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1037..1202
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 148..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 901..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..864
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 930..946
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1226 AA; 137225 MW; E3CFEDCF3A3C3391 CRC64;
MEDQVDFDIN ESLKLYLSDV TTITTPEASP ELIDCENDPD SLTPALVDSV LDSVIDVITE
NPEGLFRSST FDTLQFLLKT SSALSTQALA KILNLIVSGL STTADVANHD IENDEQETLP
QHKRLLEMYA FLLQWSISAV EAKAQEKSSA APARRGGKGA KSKSAAKDNA WDSSSQIQSA
MDVMCRVMKL KLNRIFQTTS DRDTFINLFT RSIYLIMESE ARVKITAVRM FCFKVLCVAV
KHHGHALGAQ TSIVQNLTYF EHLSEPMAEF LHILSEQYDY PQLSAEILRE LAAKEFSQND
NKGPKSVSAF IIKLSELEPR LVIKEMGLLA KFLDSEAHTL RCAVIEVCGN LLADLSRQEE
KTETTKIQIN AFFDTLEQRF LDTAPFCRVR AMQVLTKICD LEQKFPKRRQ NAAELAMQSL
QDKSSNVRRN AIKLLRKLVS SHPFSLMHGG QLSHKEWTER LEAVESQLDA LKPPPDSPGL
AKTAAGEEQV DQELLDDATQ AVEEPRELTE EEKIAAVKKA QEEAATSEVI GKLQLTRKYY
LEALRFIETI HDASEIAVQL LSSPNKTEVI DVMDFFVTID AFKVETARKG IRRMMRLIWT
KGNSDEGKGV QNHLIDNYKN LFFDAPDMFS TNDAANFVAR NMISLTFGAT PAELTSLEQL
LSTMFKAGHI SELVIAKLWQ VYGVNKEISK AQRRGAIIAL GMIALASPEV VVKEMDTMLR
VGLGQLGRTD FVLAKFTCVA LRRMIPTTKK VQEKTASAGL SKMSNNHEVL RMLASILLTT
SASKDWYGMA EQAISAIYVL SDHPDVLCSE VLRQKTRLVF QQTKDLSSLS RTPSPEPDAM
DIDGEEQVTN PETEPHEPEP TESKQEKPSI ALSQLLFAVG HIAIKQIVHL ELCELDFKRR
KQDQEKNKPE ANPSPEKSSG PTAGQRKRTA AEEVLAEKQK EEEKDELDLI GGTTEDDFTE
AIAHIREREL LYGPHSLLAN FGPLVTEICA NNTAYKDRNL QAQATLCLAK LMCVSSEYCE
KNLPLLITIL ERSMDPIVRS NAVIALGDMA VCFNHLIDEN TDFLYRRLND GDESVKRTCL
MTLTFLILAG QVKVKGQLGE MAKCLEDGDK KIADLARMFF TELATKDNAV YNQFVDMFSV
LTQEGPLEGG VMEEEAVKRI LKFLCGFIEK DKHAKNLAEK LAARLNRCVN KRQWDDTAYA
LSLLQHKNED IARKIQEGYR VVETEA
//
