ID A0A0D2AXI2_9PEZI Unreviewed; 986 AA.
AC A0A0D2AXI2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
GN ORFNames=PV09_04734 {ECO:0000313|EMBL:KIW03889.1};
OS Verruconis gallopava.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Sympoventuriaceae; Verruconis.
OX NCBI_TaxID=253628 {ECO:0000313|EMBL:KIW03889.1, ECO:0000313|Proteomes:UP000053259};
RN [1] {ECO:0000313|EMBL:KIW03889.1, ECO:0000313|Proteomes:UP000053259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 43764 {ECO:0000313|EMBL:KIW03889.1,
RC ECO:0000313|Proteomes:UP000053259};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Ochroconis gallopava CBS43764.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KN847542; KIW03889.1; -; Genomic_DNA.
DR RefSeq; XP_016213758.1; XM_016358140.1.
DR AlphaFoldDB; A0A0D2AXI2; -.
DR STRING; 253628.A0A0D2AXI2; -.
DR GeneID; 27312707; -.
DR VEuPathDB; FungiDB:PV09_04734; -.
DR HOGENOM; CLU_002794_11_2_1; -.
DR InParanoid; A0A0D2AXI2; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000053259; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053259};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 131..422
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 986 AA; 110690 MW; DD15227DDA0FA3AC CRC64;
MEDDLYDEFG NYIGEDVSEE EEEEALPTQA GDAYLDDVDD AHTEAHDGTV MEVDDGPSNA
VILHEDKQYY PTAQQVYGRD VETMVQEEDT QALSQPIVEP IVVKKFAVEE SDLPPVYYSR
EFMTDLMNFP DKVRNISLAG HLHHGKTALM DMLVLETHNI QDRLDKKQGK SREDQLRYTD
THVLERERGL SIKTAPMSLV LENNKGVSHL LHILDTPGHV NFADEVASSL RLSDGVVLVV
DVVEGVQSMT EMVIKHAVLD DLPVVLVINK MDRLILELKL PPQDAYHKLK YVVEEVNTII
ENTIPGRGES RRLSPEKGNV AFACSSMGWC FTLRSFAKMY TEAYPKTKVH PEDFARRLWG
DIYYNPSSGK FSRKGVEEGS RRSFVNFVLD PIYKLYSHTI SEGPHDLDET LQSLGIKLKP
SELRCDARVL LKKVCEQFFG PSRGFVDMVA EHIPSPEQGA KRFIEKYYTG SMDTKTAKSM
QQCHQDGPLV VHITKLFNTV DAKRFNAFGR VLSGVARPGD QVRVLGEGYT VEDEEDMVNA
TISDTWIAES RYNVPVSGVP AGNWVLLGGV DNSIVKTATI LPETLPDGDE AYIFKPIRHW
FESVFKVAVE PINPSELPKM LDGLRRINKS YPLITTKVEE SGEHIILGTG ELYMDCVLHD
LRRMYAEMEI KVSDPVTRFC ETIVETSAMK CYALTPNKKN KITMVAEPLD PGIAEDIESG
AVNIKDPVRV VGKFFEEKYE YDLLASRNIW AFGPDDMGPN ILQNDTLPSE VDAKLLRSVR
DTIKQGFSWA TREGPLCEEP IRNSKFRLTD ISLAPEAIFR GGGQIIPTAR RACYSSFLMA
SPRLMEPVYE CTVIGPIDAV SSLYTVLQRR RGHVLQDAPI AGTPLYRAKG LIPVIDSFGF
ETDLRIHTQG QATVSLVFDR WSIVPGDPLD RDIKLRPLEA ASAMATARDF VLKTRRRKGL
SEDVTIGKFL EPELFAQLKE SGVLEI
//
