ID A0A0D2B4L1_9EURO Unreviewed; 611 AA.
AC A0A0D2B4L1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=RNA-binding protein VTS1 {ECO:0000256|ARBA:ARBA00024136};
GN ORFNames=PV08_06654 {ECO:0000313|EMBL:KIW13873.1};
OS Exophiala spinifera.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW13873.1, ECO:0000313|Proteomes:UP000053328};
RN [1] {ECO:0000313|EMBL:KIW13873.1, ECO:0000313|Proteomes:UP000053328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW13873.1,
RC ECO:0000313|Proteomes:UP000053328};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala spinifera CBS89968.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Monomer. Binds to RNA. {ECO:0000256|ARBA:ARBA00024046}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the VTS1 family.
CC {ECO:0000256|ARBA:ARBA00007325}.
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DR EMBL; KN847496; KIW13873.1; -; Genomic_DNA.
DR RefSeq; XP_016234089.1; XM_016380987.1.
DR AlphaFoldDB; A0A0D2B4L1; -.
DR STRING; 91928.A0A0D2B4L1; -.
DR GeneID; 27333737; -.
DR VEuPathDB; FungiDB:PV08_06654; -.
DR HOGENOM; CLU_017632_0_0_1; -.
DR OrthoDB; 1351201at2759; -.
DR Proteomes; UP000053328; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR CDD; cd09556; SAM_VTS1_fungal; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037635; VTS1_SAM.
DR PANTHER; PTHR12515:SF5; PROTEIN SMAUG; 1.
DR PANTHER; PTHR12515; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053328};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 547..605
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 522..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..537
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 66239 MW; F9840FF1ECF5FE93 CRC64;
MASNIIGNRN STPEASKTSL RPPSSRTIGS SNTHNQPVRS SADMSFTSPL SARSIRPASE
VLYNQQSQQG GLDDSSRLGE QWIQDIEQYE TMLEEMAAAT LDQDFKDELS AIEQWFRVLS
EAERTAATYA LIQQTTQMQQ RFFAQVLNQM SKSHPISGVL SPTNFGEKDP MSSRLSDAMS
KLNVDDRRTS MGRPPVSPAG NKRNSGLDQS TIHAMFPDAV AAIQQQKAEY AQQTGNPPPS
NRNSTVIGDR SSLVAPTISA PRENKTEALS WRQGGDSQQP PISRPKSSSG YQSQPPMGQF
SQPPASATLR SPRPLGTPAG NIQSTTLTAP EPNEMPMLSP YNVGNQSWAS MTNTPMVPNF
NQSNTHNDMV ANATAMKLAA LSTVTNRIAL DDAKKFRRAR SNEPSPQSHP PLTPGLQSSG
IPGINTIMVN DQGQILNAQQ IAALQAQQIA ANQGRRSRPN SPGLPLQTPL GQASFASPQH
NGFLAAYDGN PIMMGAGMPG LIPTMGPFGG AEGYLSDHSE IARGRSPRGR RGSSKPPEDP
TDPGLLQDIP SWLRSLRLHK YTDNLKDLKW QELIELDDKG LEARGVNALG ARNKMLKVFE
QVKEAQSEGK L
//
