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Database: UniProt
Entry: A0A0D2B5G2_9EURO
LinkDB: A0A0D2B5G2_9EURO
Original site: A0A0D2B5G2_9EURO 
ID   A0A0D2B5G2_9EURO        Unreviewed;       378 AA.
AC   A0A0D2B5G2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   18-SEP-2019, entry version 19.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=PV07_04353 {ECO:0000313|EMBL:KIW32837.1};
OS   Cladophialophora immunda.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW32837.1, ECO:0000313|Proteomes:UP000054466};
RN   [1] {ECO:0000313|EMBL:KIW32837.1, ECO:0000313|Proteomes:UP000054466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW32837.1,
RC   ECO:0000313|Proteomes:UP000054466};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; KN847041; KIW32837.1; -; Genomic_DNA.
DR   RefSeq; XP_016253053.1; XM_016391151.1.
DR   EnsemblFungi; KIW32837; KIW32837; PV07_04353.
DR   GeneID; 27343547; -.
DR   EuPathDB; FungiDB:PV07_04353; -.
DR   OrthoDB; 1034517at2759; -.
DR   Proteomes; UP000054466; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054466};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361}.
FT   DOMAIN       48    349       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   378 AA;  40545 MW;  088F07BB0BA7C907 CRC64;
     MPAVDAPAHA PGEDVRVLGY DPLIPPALLQ AEIPASQSSV ETVAKGRREC KEIIHQRDDR
     LLVMVGPCSI HDPATALEYA GRLKELSEKL SADLCIIMRA YLEKPRTTVG WKGLINDPDI
     DESYKINKGL RVSRQLYADL TSMGMPIASE MLDTISPQFL ADLISLGAIG ARTTESQLHR
     ELASGLSFPM GFKNGTDGSL SVAIDAVGAA AAKHYFMGVT KQGLAAITKT SGNEDGFVIL
     RGGSKGTNYD AESVKAARAA LKSKGQREVM MIDCSHGNSK KNHKNQPLVA QAIGDQLRQG
     EDAIVAVMIE SNINEGNQKV PPEGGLTSLQ KGVSITDACI NWESTVEVLE QLAEAVRARR
     QVRKSQQNGT NGVSNGHH
//
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