ID A0A0D2B6F7_9EURO Unreviewed; 526 AA.
AC A0A0D2B6F7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PV08_07062 {ECO:0000313|EMBL:KIW14280.1};
OS Exophiala spinifera.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW14280.1, ECO:0000313|Proteomes:UP000053328};
RN [1] {ECO:0000313|EMBL:KIW14280.1, ECO:0000313|Proteomes:UP000053328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW14280.1,
RC ECO:0000313|Proteomes:UP000053328};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala spinifera CBS89968.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; KN847496; KIW14280.1; -; Genomic_DNA.
DR RefSeq; XP_016234496.1; XM_016381394.1.
DR AlphaFoldDB; A0A0D2B6F7; -.
DR STRING; 91928.A0A0D2B6F7; -.
DR ESTHER; 9euro-a0a0d2b6f7; Fungal_carboxylesterase_lipase.
DR GeneID; 27334145; -.
DR VEuPathDB; FungiDB:PV08_07062; -.
DR HOGENOM; CLU_006586_15_0_1; -.
DR OrthoDB; 3085104at2759; -.
DR Proteomes; UP000053328; Unassembled WGS sequence.
DR GO; GO:0004104; F:cholinesterase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR000997; Cholinesterase.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR PRINTS; PR00878; CHOLNESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000053328};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 25..526
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005112826"
FT DOMAIN 32..481
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT ACT_SITE 229
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600997-1"
FT ACT_SITE 345
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR600997-1"
FT ACT_SITE 442
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR600997-1"
SQ SEQUENCE 526 AA; 57167 MW; E10652927A902E8E CRC64;
MVKFYLYSLS LALSLLNATS SSFAQQVSQN PPSATIDSGV VVGLATSLSE GGFPINKFLG
VPFAASPVRF QPPAKPTPWT KPLEASKYRP ACIQQLATQD GIPPAQVASW SNTPPPPAGE
SEDCLNVNIY APNSTGMKPV MVWIYGGGFA LGFNSDPRWD GSFMAANQDV VVVSVNYRTN
VFGFPMSPQL PLSQQNLGFL DQHFALDWVQ RNIHSFGGDP KRVTIFGESA GAASVDALVT
SYDENPPFVA AIMESGQITF YPNTPNATAP WKNMVARLNC SSAPDVLACV RAIPATEIKS
TIEGPGNFAF GPVRDNITFI SHSGVARQQR KIAQVPILIG NNFQEGRLFV TAYNSTQQYL
ERTLPNMNQS FYNRVLTAYP LGSPGISNEF ERAAAIDTDF RFLCPTAQVA NYSSMAGLQT
WRYLFNASFP NTQLFPDAGV YHSSEISEVF GTYPRGDVTT KQESLSRYMQ KAWADFAKNP
TGGPGWKAVP NVAVLGQSEQ EIEQNMPGTT IDNICALYMP LYSALA
//
