ID   A0A0D2B6I5_9EURO        Unreviewed;       849 AA.
AC   A0A0D2B6I5;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE            EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN   ORFNames=PV08_07087 {ECO:0000313|EMBL:KIW14305.1};
OS   Exophiala spinifera.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW14305.1, ECO:0000313|Proteomes:UP000053328};
RN   [1] {ECO:0000313|EMBL:KIW14305.1, ECO:0000313|Proteomes:UP000053328}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW14305.1,
RC   ECO:0000313|Proteomes:UP000053328};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala spinifera CBS89968.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC         in alpha-L-rhamnosides.; EC=3.2.1.40;
CC         Evidence={ECO:0000256|ARBA:ARBA00001445};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KN847496; KIW14305.1; -; Genomic_DNA.
DR   RefSeq; XP_016234521.1; XM_016381419.1.
DR   AlphaFoldDB; A0A0D2B6I5; -.
DR   STRING; 91928.A0A0D2B6I5; -.
DR   GeneID; 27334170; -.
DR   VEuPathDB; FungiDB:PV08_07087; -.
DR   HOGENOM; CLU_007933_1_0_1; -.
DR   OrthoDB; 67137at2759; -.
DR   Proteomes; UP000053328; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR035396; Bac_rhamnosid6H.
DR   InterPro; IPR035398; Bac_rhamnosid_C.
DR   PANTHER; PTHR34987:SF4; ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR34987; C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED; 1.
DR   Pfam; PF17389; Bac_rhamnosid6H; 1.
DR   Pfam; PF17390; Bac_rhamnosid_C; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053328};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..849
FT                   /note="alpha-L-rhamnosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002249529"
FT   DOMAIN          419..657
FT                   /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT                   /evidence="ECO:0000259|Pfam:PF17389"
FT   DOMAIN          767..834
FT                   /note="Alpha-L-rhamnosidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17390"
SQ   SEQUENCE   849 AA;  91088 MW;  FDF0882E63AC28A4 CRC64;
     MHTAHLLATL VTLYLGILYA DGRAFSPWSR DGSFNPGNAS KYKGDDLAPV YYAVGPEPTI
     NTTVAWTAST IISLNASSTV ATLDYGSEAA GIPFIYVQSL SGPAQLELRY GEQFPALQNP
     NGDGPWTFIN GLTNTFRTET LNITTTGRVE SFFVQGGQRW QSVRLLTEAP ISLSAGLRLT
     SDHLAPAQLS GRFSASNPLY EEIFDLGGRT VQAACIDRGA APSVWEVTSD GVRVRGQQTS
     QSIVGINFSN YTISFMTKVI QSGTAFRVAS GVFPYGAYFV LTTQSTPYLD TNRTVLPANS
     LIWNYGWSMV NQSTLAVPAV HVLPLKTPIV PDTWYNIALE ITSTGYNISL DGRSLAFISS
     EEILALLNPL WGSPTWYSGT WGFGPFQGQD AFFKDVKVIA KNGTVLYNNS MMSSDVLAEY
     SVLPNPNPVC MDGAKRDRLV WVGDFAHTCR VVLHSTNRLD YLRGSISQAL AWASDHGPTA
     GFVGMDSPLG TTALSKAAYS DHLYSLFDYQ DLFILALGDY YWATGDLAFI KAHWSQIGAA
     VDGRLTLNNP TTSLSETPDI QGIYFLGPAN GSAASAVNVL ALQRAASLAS AVGDVASVHK
     WTAVAQSIST AINSLLWNPE SGVYSLSTAY PDDFSLAAIA FTIRAGIANA TQAAAMIQKV
     PQLRLGIGFK DSSMVNSTAT TQLSPNTQGF LLEALFLAHR DFGTPLDSAR VLLDTFWAAM
     VTQNQYYSGA SWEYTYPDGS PGIDLFTSLS DPWGAAPTYL LSEYVLGISA TKPGYTSWSM
     QPLVEGLGLT HASGTVPTPS GPIEANWHIV GNNATICVSA PKVSRGQIVF GGQKFAVSGG
     QQHCVNVAL
//