ID   A0A0D2BHA7_9EURO        Unreviewed;       949 AA.
AC   A0A0D2BHA7;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV08_02651 {ECO:0000313|EMBL:KIW18363.1};
OS   Exophiala spinifera.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW18363.1, ECO:0000313|Proteomes:UP000053328};
RN   [1] {ECO:0000313|EMBL:KIW18363.1, ECO:0000313|Proteomes:UP000053328}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW18363.1,
RC   ECO:0000313|Proteomes:UP000053328};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala spinifera CBS89968.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; KN847493; KIW18363.1; -; Genomic_DNA.
DR   RefSeq; XP_016238579.1; XM_016377009.1.
DR   AlphaFoldDB; A0A0D2BHA7; -.
DR   STRING; 91928.A0A0D2BHA7; -.
DR   GeneID; 27329734; -.
DR   VEuPathDB; FungiDB:PV08_02651; -.
DR   HOGENOM; CLU_008136_1_0_1; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000053328; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053328}.
FT   REPEAT          474..512
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REGION          335..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..350
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..383
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        386..404
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   949 AA;  105537 MW;  16FE606F34776C70 CRC64;
     MAWQPEEEAL RQLSEYLKNS LSGHDRNKQK EAELMIMNAR NNNDYVNYLT YIFTTPQLGQ
     QLQLNTPSLF LIRYAGGVNL KNHIKLFYSN IPKDQLAYVK AATLTVLRDP NPQLRGFAGT
     VITEIVTQGG LLQWPEILQE LLSLVDNSAG NAPAETQEGA MSALAKVCED NRKLLDKEFQ
     GQRPMTVIVP KLLEFATHSN PKIRVLALST LKTFIPQKSQ VLFSALDIYL QTIFQLATDP
     DVQVRRIVCQ SLVQLVETRP DALSPHLDGL VNYILTQQQS SGNPDLALDA AEFWLSVGEQ
     DQLRDRMGPY LNKIIPVLLA GMVYGEDEVF RLGGDENDAD VEDRSEDIKP QFAQTKAGRG
     VKSEKEDSAP GTPQANGTPS KNDDLSDGEI EEEDEDEEWD DDDPENAWSL RKCSAAALDV
     FAVNYGVAVF DIILPYLKEN LSHSLWPKRE AAVLALGAIA EGCMDVVSPH LPELVPFLIS
     LLSDEEPVVR QITCWCLARY SEWASRLESQ ADKQRYFEPM MEGLLHRMLD KNKKVQEAGA
     SSFASLEEKS GEKLKPYVEP ILRQFTECFK RYKDKNMYIL YDCLQTLADS VGQEIAKPEL
     VNLLMPVLIE RWNKIQDDSR EMFPLLGCLG YIAMAYGDTF AQFAAPIFDR CIKVIYSNLQ
     QHMAFVSGQT VDQPDKDFIV TALDLLSAII QAISPEKSAP LVQNSQPQFF DLLSFCMEDP
     TTDVRQSAYA VLGDCAIALF NTLDPYLAKL LPVSIRQLDL DAMPDDDSEN SFNVLANVCW
     SLGEIAARAS TSRISPFIEP LYRGLVTIIK NEEVPDPASE NAATALGRLG LVCPEHLAPF
     LSEFAEPFLS SMSKVSTSHE KASAFLGFNN VIERNPQAME ASLGLYFSAI AQFPQKGKQG
     ADYSEVRSSF GRVIQGYVGL IGQDGFRNFL GGLSAPVRQK LSDGYGLGS
//