ID A0A0D2BKF0_9EURO Unreviewed; 437 AA.
AC A0A0D2BKF0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=PV06_09864 {ECO:0000313|EMBL:KIW37882.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW37882.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW37882.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW37882.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; KN847342; KIW37882.1; -; Genomic_DNA.
DR RefSeq; XP_016258098.1; XM_016411344.1.
DR AlphaFoldDB; A0A0D2BKF0; -.
DR STRING; 215243.A0A0D2BKF0; -.
DR GeneID; 27361938; -.
DR VEuPathDB; FungiDB:PV06_09864; -.
DR HOGENOM; CLU_030894_0_5_1; -.
DR OrthoDB; 3280806at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09280; RNase_HI_eukaryote_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 2.
DR InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR InterPro; IPR011320; RNase_H1_N.
DR InterPro; IPR037056; RNase_H1_N_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF01693; Cauli_VI; 2.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF55658; L9 N-domain-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053342}.
FT DOMAIN 238..388
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 48567 MW; D21DC3CDF9DABE03 CRC64;
MAQPSPLPKP SHSGRSSPSL TPTNAAAGQK RKRAVERKFY AVREGKEPGI YETWPECLSQ
VKGFKGAVFK TFQNLHEAQA WMEGKPLTES RVNPADQKYY AVQSGKVPGV YTDWTQAQAQ
IRGFSKPKHK KFNTRIEAEA FVAAGKKPSG PDQAQNLTPE EEIRRLIVRN SAPGLQINGT
YAPTDKDGNP YDVARRPLPP GAEDGYDPNV KLTPDGRIVD RTEDEKNRTK MMAREKNPPG
MLRIYTDGSS LKNGQAGARA GVGVFFGPQD PKNVSEALKG SKQTNQRAEL TAILRALNIA
PLHREITIYT DSKYSIDCVT NWYKNWKKNN WTNSKGKPVE NKDLVVEIRD KIEEREQFSK
GTYFVWVKGH SDNPGNIAAD RLAVAGAMNG RGVDSKDGKE EESVPDDVKQ RNGAERDDED
DETKEAFGAM NEAMEDE
//
