ID A0A0D2BQ51_9EURO Unreviewed; 664 AA.
AC A0A0D2BQ51;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:KIW54666.1};
GN ORFNames=PV05_07013 {ECO:0000313|EMBL:KIW54666.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW54666.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW54666.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW54666.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847320; KIW54666.1; -; Genomic_DNA.
DR RefSeq; XP_013315250.1; XM_013459796.1.
DR AlphaFoldDB; A0A0D2BQ51; -.
DR STRING; 348802.A0A0D2BQ51; -.
DR GeneID; 25328921; -.
DR HOGENOM; CLU_000022_3_3_1; -.
DR OrthoDB; 45466at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KIW54666.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342}.
FT DOMAIN 37..94
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 101..477
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 549..619
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 664 AA; 73451 MW; DCBF5AB18390F670 CRC64;
MSATQKPLWV HPAPQFSQAD GFRRLINRKY GLKLETYDDL HRWSVDELET FSVEVWTFCG
MVYSKPPTAT AVGLESMWPR PQWFPGARLN YAENMLATGL AVHPDAIAIS ACREGGTEWR
HLSWMQLRAE VERYVSAFKQ AGISKGDRVA AVMTNSPEAL LVLLASAAVG AIFSSTAPDM
GQKGITERYL QIRPKVLFVD TEVLYGGGEK DLRQKVSSVV RSLQASVSEL EKVVVTRGHL
WSGTNSMSLE TFLQAPRQEL IFEQVEFDHP VYILYSSGTT GPPKCICHAG GAALLQQKKD
LMLIKDMGPN SVYYQYTTTG WMMWNYLVAG LSTGARIVMY DGSPSHPSPA YQVQLLSEQG
VTEWGTSPKF LAALKQHGLG AMPNLENLAL TLVTGSPLSV ELSEWFYQKF PRHVATFSSS
GGTDLVSAIV NGSMLRPFYA GELATKCLGM AVEIWDASGK NIEDTGEKGD LVITKPFFSM
PVTFWGENGM EKYRKAYFDQ FPGVWCHGDF ISKNPATKGF TILGRSDGVL NPGGIRFGTA
ELYGVVDKFK EVEDCIAVGQ RREHDSDERV LLFLKLAQKP MSKELEQRIR TAIRTELSAR
HVPSYILEVA DIPYTANGKK IENVVKDVVS GRVPKIGGTA VNPECLEEYK AFANLPPLPA
KARL
//
