ID A0A0D2BYK6_9EURO Unreviewed; 988 AA.
AC A0A0D2BYK6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=PV06_06052 {ECO:0000313|EMBL:KIW42507.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW42507.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW42507.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW42507.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847336; KIW42507.1; -; Genomic_DNA.
DR RefSeq; XP_016262723.1; XM_016407119.1.
DR AlphaFoldDB; A0A0D2BYK6; -.
DR STRING; 215243.A0A0D2BYK6; -.
DR GeneID; 27358126; -.
DR VEuPathDB; FungiDB:PV06_06052; -.
DR HOGENOM; CLU_002472_7_3_1; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342}.
FT DOMAIN 658..674
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 838..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 930..966
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..988
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 988 AA; 109854 MW; 4A67B86A1FDDEE41 CRC64;
MRASRALSTT SRLTRKTQGG STGGSNTRPR SRRASTSMGH ANSEIVCAVA ECRGISPVVG
LSFVDISTCE AVLCQFSDTQ TYARTCHKIS VYGPSEILYM PNAADSKLVS IISENLDVEE
NDISMHNVDR KHWSESAGHD YIEFLACPND LDALKIALTG NNCATCCFSA VCNDNNRIPT
AKLTLQAMRY TEHALQKIFA RKSLRVRFET AEGSMMIDPS TIASLELVQN AQNAKSRECL
LGLLNNTLTP MGARFLRANI LQPSTDVEKI NKRQDAIEQL SKQEHTLSAL RDAMRSFVDS
DRILAALVVM PTKPDSTYTE QSVNNVLMLK TFVDSIAPIW RALGNSNCEE LSNIYQLCSS
ENYAKVENII LETINEDVHY STKPTDLRNQ RVYAIRAGVD SVLDVARQTF KEINEDVYRM
VEELKVAHEL PSCDLKFDTA RQYFLRINCD DSFSQNLPEI LINIFRRPKY IECQTLDLVK
MNQKMRNAHA DIIHLGDGAV QQLIGTVRCE IHPLFKISEA IALLDMLSSL AQLSIINNYT
RPEITDTLGL EACRHPLREK IQLERFVPNH VYATQQTRFQ IITGCNMSGK STYIRSIALA
VIMAQMGSFV PASSASLPII RNLFARASTD DSIEANISSF SGEMREMAFI LRTISEQSLV
IIDELGRGTS TTDGLAIAIA IAEALVESKA LVWFVTHFRD LPRILAERAG VVNHHLAVDI
GDDLSKMTMR YQISDGYEEK RFYGLALAKV VGLPEPVLDV AESVSRSLND RNDAQKRNPK
AAAEAKRRKL LLNLREHLVQ ARDSCATGQT ETADRRAWLM RLQDDFALGM RGIDIEAGEV
VEGDGDGDTE ATPSDEHTDT VTDTDTPGRR GRHKDAGIIM PGASMMEEGG MQSNGKHHAE
TLSDTRSSSS SSVVEVVDRS ATVQGIKRED FEERHEEEGV AVAAEEHDSD TTTHVDTTTH
GSDDHYADEY DDDDDDDEEM MMLDHEPW
//
