ID   A0A0D2CAZ3_9EURO        Unreviewed;       580 AA.
AC   A0A0D2CAZ3;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=NCS1 nucleoside transporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV07_07917 {ECO:0000313|EMBL:KIW28238.1};
OS   Cladophialophora immunda.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW28238.1, ECO:0000313|Proteomes:UP000054466};
RN   [1] {ECO:0000313|EMBL:KIW28238.1, ECO:0000313|Proteomes:UP000054466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW28238.1,
RC   ECO:0000313|Proteomes:UP000054466};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
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DR   EMBL; KN847043; KIW28238.1; -; Genomic_DNA.
DR   RefSeq; XP_016248454.1; XM_016395035.1.
DR   AlphaFoldDB; A0A0D2CAZ3; -.
DR   GeneID; 27347111; -.
DR   VEuPathDB; FungiDB:PV07_07917; -.
DR   HOGENOM; CLU_021555_2_1_1; -.
DR   OrthoDB; 1218881at2759; -.
DR   Proteomes; UP000054466; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   PANTHER; PTHR30618:SF0; PURINE-URACIL PERMEASE NCS1; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        459..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        489..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   580 AA;  64050 MW;  4CE3A888E6C28C24 CRC64;
     MVKFSAETIK APFESKEAFL RFVRTDSPGG VVSTPWSNKD LEPTPPEHRH WRWFNLPFYW
     MTTAFGTAGW NLAASLIATG LTWRQSFAAC ALGVLISGIA VVLAARCAAV YHIGYPVIAR
     SIFGLYGSFF FVFFRATIGT IWYGINTFYG ANLMSTCLLC MFGHKWKNFP NHLPESASIT
     SAQLLCFFLV WFIQAPFTLI HPRNAHWVFV VKGSVMPVAI FGLFGWCMAN GAGISAIGNP
     LAKQADTPLG WAMLSGINSV IGISAGLLVS QPDMARYSVN PRAAGIPQGF FLAIPKLLVL
     FLGLASTASM QGKWGTAYWN IWDLNNAILE HNWTAAARTA VFLESLCFFF STVGTNIGAN
     LIPFSADVAG LLPRYITIVR GQVLCALIAV VILPWKLVAS AQAFLTFLGA YNIFMGPILG
     LMAADYFIVR KGNIHIPSLY QPIKGTLYMF YHGFNLRSHL AWTGGMLLGL PGLIAAYQPN
     AVGESAKRMY TMAWILTTAM TVFLYLVLCY IFPVQTYPTA YSDVPVKWEY LGATEGYFDG
     EERRPTVFDE LHGLPMQEEN IEKEAITIDM EKIVGSKTEV
//