ID A0A0D2CBL0_9EURO Unreviewed; 62 AA.
AC A0A0D2CBL0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=General transcription and DNA repair factor IIH subunit TFB5 {ECO:0000256|RuleBase:RU368032};
GN ORFNames=PV07_07498 {ECO:0000313|EMBL:KIW27790.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW27790.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW27790.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW27790.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: In NER, TFIIH acts by opening DNA around the lesion to allow
CC the excision of the damaged oligonucleotide and its replacement by a
CC new DNA fragment. In transcription, TFIIH has an essential role in
CC transcription initiation. When the pre-initiation complex (PIC) has
CC been established, TFIIH is required for promoter opening and promoter
CC escape. {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBUNIT: Component of the 7-subunit TFIIH core complex.
CC {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU368032}.
CC -!- SIMILARITY: Belongs to the TFB5 family.
CC {ECO:0000256|RuleBase:RU368032}.
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DR EMBL; KN847043; KIW27790.1; -; Genomic_DNA.
DR RefSeq; XP_016248006.1; XM_016394587.1.
DR AlphaFoldDB; A0A0D2CBL0; -.
DR STRING; 569365.A0A0D2CBL0; -.
DR GeneID; 27346692; -.
DR VEuPathDB; FungiDB:PV07_07498; -.
DR HOGENOM; CLU_166246_2_0_1; -.
DR OrthoDB; 419at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0000439; C:transcription factor TFIIH core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005675; C:transcription factor TFIIH holo complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.1220; TFB5-like; 1.
DR InterPro; IPR035935; TFB5-like_sf.
DR InterPro; IPR009400; TFIIH_TTDA/Tfb5.
DR Pfam; PF06331; Tfb5; 1.
DR SMART; SM01395; Tbf5; 1.
DR SUPFAM; SSF142897; TFB5-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|RuleBase:RU368032};
KW DNA repair {ECO:0000256|RuleBase:RU368032};
KW Nucleus {ECO:0000256|RuleBase:RU368032};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW Transcription {ECO:0000256|RuleBase:RU368032};
KW Transcription regulation {ECO:0000256|RuleBase:RU368032}.
FT COILED 25..52
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 62 AA; 7116 MW; 05EC8DC61A7F1862 CRC64;
MAMVRKIDRE SGHAYILEEI DDRTCLVKEN KVEEIKAKVK ELMDAAMGMD EDVNDDKDSD
LD
//
