ID   A0A0D2CC28_9EURO        Unreviewed;       907 AA.
AC   A0A0D2CC28;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=MaoC-like domain-containing protein {ECO:0000259|Pfam:PF01575};
GN   ORFNames=PV04_10757 {ECO:0000313|EMBL:KIW62596.1};
OS   Phialophora macrospora.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX   NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW62596.1, ECO:0000313|Proteomes:UP000054266};
RN   [1] {ECO:0000313|EMBL:KIW62596.1, ECO:0000313|Proteomes:UP000054266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW62596.1,
RC   ECO:0000313|Proteomes:UP000054266};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|ARBA:ARBA00005005}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
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DR   EMBL; KN846963; KIW62596.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2CC28; -.
DR   STRING; 5601.A0A0D2CC28; -.
DR   HOGENOM; CLU_010194_18_0_1; -.
DR   OrthoDB; 2140828at2759; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000054266; Unassembled WGS sequence.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   CDD; cd03448; HDE_HSD; 1.
DR   CDD; cd05353; hydroxyacyl-CoA-like_DH_SDR_c-like; 2.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR002539; MaoC-like_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR45024; DEHYDROGENASES, SHORT CHAIN; 1.
DR   PANTHER; PTHR45024:SF2; SCP2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00106; adh_short; 2.
DR   Pfam; PF01575; MaoC_dehydratas; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140}.
FT   DOMAIN          783..894
FT                   /note="MaoC-like"
FT                   /evidence="ECO:0000259|Pfam:PF01575"
FT   REGION          765..790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   907 AA;  98320 MW;  83F3956E978E6A0B CRC64;
     MASQLRYDNQ VAIVTGAGNG LGKQYALFLA SRGAKVVVND LGGSFNGKDA GGGGDARVAD
     VVVKAIRDAG GTAVANYDPV QKGDRIVKTA IDAFGRVDIL INNAGILRDI TLRNMKHEDW
     DVIMDVHVHG AFKTARAAWP YMRKQRYGRI INTSSSSGLF GNFGQSNYAA AKMALVGFSE
     TLAKEGAKYN ITCNVLAPGA ASRLTQTVWT QDMMEVMKPD WVVPLVGVLV NETCRESGSI
     FEAAAGHYSK IRWERSKGFL TNPESLTADV VLEKWDKIVD WNGAEHPSEP APILQMLEKA
     KTLPRITSSS SKKVSFKDQV VLVTGGGAGL GRAYSLLFAK LGAKVAVNDV KDADRVAAEI
     KSNGGEALAL PLSVEEGEAI VRKVVETYGR IDVVINNAGI LRDKAFTNMT DEQWYAVMNI
     HLRGTYLITR AAFPVMLKQR YGRIVNVTST SGIYGNFGQA NYAAAKCGIV GFTKTIAREG
     AKYNVVVNTL APTAGTDMTR TVWPEENVRL IKPDYVAPLV AALCSERPPA TGQIFESGCG
     WIGATRWQRA RGVDFEHDKG VPSAEQVAEA FSEICNFENG QADNPDTPQD GSKYTMGNVL
     KNPKIAAGLS QENRANRKYI AKIQEAMSMK PTPSTYTYDD RDVILYNISM GAHRTDLDLV
     YENAPNFQVL PTFGIVPTYT AKTPWSIKDI VPNYDQRMLL HGEQFLEIKQ FPIPTSGILK
     TETRLIEVVD KGNAALVRRG STTVDSAGKP VFYNENVAFI RGAGNFGGQK KPSDRGASTA
     ANTPPSRAPD KVVAEKTSDD LAALYRLMGD RNPLHIDPQF SAAGGFKVPI LHGLATFGIS
     GKHVFQAYGP FKNIKVRFSG TVLPGQTIVT EMWKEGGKVI YQAKVKETGK SCISNAAVEL
     LQGSSKL
//