ID A0A0D2CI52_9EURO Unreviewed; 314 AA.
AC A0A0D2CI52;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=GTP-binding protein {ECO:0000256|RuleBase:RU367014};
GN ORFNames=PV07_05632 {ECO:0000313|EMBL:KIW29845.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW29845.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW29845.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW29845.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: GTPase involved in activation of the TORC1 signaling pathway,
CC which promotes growth and represses autophagy in nutrient-rich
CC conditions. {ECO:0000256|RuleBase:RU367014}.
CC -!- SUBUNIT: Component of the GSE complex. {ECO:0000256|RuleBase:RU367014}.
CC -!- SIMILARITY: Belongs to the GTR/RAG GTP-binding protein family.
CC {ECO:0000256|ARBA:ARBA00007756, ECO:0000256|RuleBase:RU367014}.
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DR EMBL; KN847042; KIW29845.1; -; Genomic_DNA.
DR RefSeq; XP_016250061.1; XM_016392542.1.
DR AlphaFoldDB; A0A0D2CI52; -.
DR STRING; 569365.A0A0D2CI52; -.
DR GeneID; 27344826; -.
DR VEuPathDB; FungiDB:PV07_05632; -.
DR HOGENOM; CLU_044099_1_0_1; -.
DR OrthoDB; 33171at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:1990131; C:Gtr1-Gtr2 GTPase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR CDD; cd11384; RagA_like; 1.
DR Gene3D; 3.30.450.190; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006762; Gtr1_RagA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039397; RagA/B.
DR PANTHER; PTHR11259; RAS-RELATED GTP BINDING RAG/GTR YEAST; 1.
DR PANTHER; PTHR11259:SF1; RAS-RELATED GTP-BINDING PROTEIN; 1.
DR Pfam; PF04670; Gtr1_RagA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU367014};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU367014};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
SQ SEQUENCE 314 AA; 35745 MW; 112E9A21908CBB44 CRC64;
MDTRKRKKKV LLMGKSGSGK SSMRSIIFSN YVAKDVRRLG ATIDVEHSHA KFMGNLTLNL
WDCGGQDAFM DSYLNAQREN VFSDAEVLIY VFDIESRAVD QDLETYSQVI KALKEYSPNA
HVFCLVHKMD LVQSEHRERI YEERCRLIIA RSEGLSLETF ASSIWDQTLY KAWAGIVHKM
IPNLVVIERF LSAFAKQLKA EEIVLFERST FLTVTNVVTQ YGEDNPTVDR HERISNIMKS
YKHTAARNTR TTAASAGFLL FKVQTPRFNC FLARFTENTY IFVVIPPGEA AFNCAVLNTM
MARDAFSKKT GVEG
//
