ID A0A0D2CK71_9EURO Unreviewed; 573 AA.
AC A0A0D2CK71;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0000259|Pfam:PF00324};
GN ORFNames=PV05_11854 {ECO:0000313|EMBL:KIW50247.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW50247.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW50247.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW50247.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KN847323; KIW50247.1; -; Genomic_DNA.
DR RefSeq; XP_013310831.1; XM_013455377.1.
DR AlphaFoldDB; A0A0D2CK71; -.
DR STRING; 348802.A0A0D2CK71; -.
DR GeneID; 25333762; -.
DR HOGENOM; CLU_007946_12_1_1; -.
DR OrthoDB; 2048216at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF9; DICARBOXYLIC AMINO ACID PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..523
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62891 MW; 746483B073E1D94C CRC64;
MDKISQAPSP ELTQQITKQE GSSFELTTND GKTASPLPQE QRLHRGLKAR HIAMIAIGGA
IGNGLIIGTG LALAEAGPAP LLISYTIIGF LVFVVMTALG EMATWLPLGS GFTGYAARFV
DPALGFSLGW TYWIKYALTM PNQLTAASLV LQYWVDRDRV NPGVFIAVFL VVVVAINFFG
SAFFGEVEFW MTCVKVIVIV GLMILCIVLA LGGGPNHDRT GFRYWSDPGA FNEVILTGAS
GRFLAVWSTL ITATLAYLGT EMVGVTVGEA QNPRRTVPRA MKLTFYRILF FYVGSVLFLG
MVVPYNSEQL AFATKQSTSA SASPFVVAIQ LASINVLPGI VNACILIFLF SAANTDLYVS
SRTLYSLAIE GSAPQIFKNT NSNRIPVYAL IMSASFGLLA FMNISDDSKR IFKYLISIIT
TFGLLTWISI LVSHIYFVRA RRARDVPDTA LVYKAPLGIY GSYGSLLVLS LVLLTKNFTV
FVSSSRAGGS YGKFDYKTFI TGYVGIPIYL ILILGYKVLM RSKTVRPENA DLFGGRREIN
DEEAEFLEAR NAEMASRNRE RWGVAYRFIA WLF
//
