ID A0A0D2CKS5_9EURO Unreviewed; 1006 AA.
AC A0A0D2CKS5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=S1 motif domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV07_06389 {ECO:0000313|EMBL:KIW30665.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW30665.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW30665.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW30665.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
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DR EMBL; KN847042; KIW30665.1; -; Genomic_DNA.
DR RefSeq; XP_016250881.1; XM_016393362.1.
DR AlphaFoldDB; A0A0D2CKS5; -.
DR STRING; 569365.A0A0D2CKS5; -.
DR GeneID; 27345583; -.
DR VEuPathDB; FungiDB:PV07_06389; -.
DR HOGENOM; CLU_002333_5_0_1; -.
DR OrthoDB; 945235at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR CDD; cd09862; PIN_Rrp44-like; 1.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR022966; RNase_II/R_CS.
DR InterPro; IPR033771; Rrp44_CSD1.
DR InterPro; IPR033770; RRP44_S1.
DR PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF13638; PIN_4; 1.
DR Pfam; PF00773; RNB; 1.
DR Pfam; PF17216; Rrp44_CSD1; 1.
DR Pfam; PF17215; Rrp44_S1; 1.
DR SMART; SM00670; PINc; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 85..203
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT DOMAIN 512..846
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
FT REGION 326..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 113064 MW; 638827028FCB3550 CRC64;
MKSLKRGLAA DPNVGNISSK VFIRSTKSGR VQKVVREQYL RKDIPCSSQL CTTCASTAAP
NANGVVPKFI LSKRPTGTKA FAGGHYLVPD TNVLLSAMDL FEEPAHFHDV IILQTVLEEL
KNRSLPLYNR LMSLTQSDDK RFYLFFNEFR FETAVQRATG ESINDRNDRS VRKAAQWYTD
HLSKVTKKPP TIVVLTDDQE NRRKAKKESV TALSLREYVE GLDDADRLLD MVSQGAEAQE
VRAVQGQLFY PEYYSMSRMM TGIKAGTLHQ GVFNVSPYNY LEGTVKVPAF DKPLLVLGRE
SSNRSISGDV VVVEILPKDQ WKAPSAQILD EETVNKNDNP EDEEQDETVV TENERRALQE
EVRRAHIAGA ETKAQPTCKV VGVIKRNWRQ LVGTIDAASG SSSGNRQTTV FLVPMDKRIP
KIRIRTRQVD ELIGKRILAT IDSWDRDTRY PVGHYIRSLG ELETKDAETE ALLLEYDVQY
RPFPKTVLDC LPSEGHSWKV PAASSDPGWK GRQDLRHLFV CSIDPPGCQD IDDALHARKL
SNGNFEVGVH IADVSHFVKP NNAMDEEASS RGTTVYLVDK RIDMLPMLLG TDLCSLKPHV
ERYAFSTIWE ITPDAEVVSS SFTKSVILSK EGFSYEQAQK RIDDQSATDE LTQGMRVLLS
LSQKLRQKRM DAGALNLSSP EVRIEADSES SDSLADVKTK ASLATNSLVE EFMLLANITV
ARQIQSVFPQ TALLRRHATP PASNFSDLSE QLKKMRGFEL DTSSSKALAD SLDLCVDPKH
PFFNTLIRIM ATRCMTSAEY FCSGSHAEPE YRHYGLASEI YTHFTSPIRR YADLLVHRQL
AYAIGYEGQG SEIVDYDLRN KGKLERVCQN LNFRHRNAQL AGRASIEYYV GQALKSRAEK
SPEAAIDVDG YVMRVFENGM VVFVPQFGIE GLVRLEDFHL KSGEALKRES KFNAEAYQLT
VFEKGHEQDE VTVELFQQLK VRVSSEEKSG AREKGKRRVR IVVLSA
//
