ID A0A0D2CLL8_9EURO Unreviewed; 525 AA.
AC A0A0D2CLL8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=PV07_03655 {ECO:0000313|EMBL:KIW32083.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW32083.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW32083.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW32083.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; KN847041; KIW32083.1; -; Genomic_DNA.
DR RefSeq; XP_016252299.1; XM_016390397.1.
DR AlphaFoldDB; A0A0D2CLL8; -.
DR STRING; 569365.A0A0D2CLL8; -.
DR GeneID; 27342849; -.
DR VEuPathDB; FungiDB:PV07_03655; -.
DR HOGENOM; CLU_019748_3_0_1; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KIW32083.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
FT DOMAIN 12..230
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 333..483
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 525 AA; 58161 MW; BECBDD46EA7CAC32 CRC64;
MAASALFKSR CRRASYLNKL AKAEDLIDLF PHGSYIGWSG FTGVGYPKKV PTALADYVEK
NGLQGKLKYN LFVGASSGAE TENRWARLNM IERRAPHQVG KEIAKGINNG NIKFFDKHLS
MFPVDLMYGF YTKHKANNRL DVAIVEASAI TEDGGIIPGA SVGASPEIIQ MADKIIIELN
TSVPSFEGLH DITMTDLPPR RKPYLIMAPE DRIGTPHIPV DPERVVAIVE SDYPDQTTEN
APEDDTSQAI ARNLIEFLEH EVKHGRLPTN LLPLQSGIGN IANAVIGGLA KGGANFKNLK
VWTEVLQDSF LDLFDSGNLD FATATSIRFS PGGFQRFYDG WENYHSKLIL RSQQVSNSPE
IIRRLGVIGM NTPVEVDIYA HANSTCVLGS RMLNGLGGSA DFLRSSKYSI MHTPSTRPSK
TDPTGVSCIV PMCTHVDQTE HDLDVVVTEI GLADVRGMCP RERAREIIKQ CAHPDYRPIL
QDYFDRAEYE CLKKGMGHEP HLLFNAFDMH KNLVENGTMK ISGWK
//
