ID A0A0D2CNN6_9EURO Unreviewed; 522 AA.
AC A0A0D2CNN6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE RecName: Full=Catalase core domain-containing protein {ECO:0000259|SMART:SM01060};
GN ORFNames=PV07_03262 {ECO:0000313|EMBL:KIW31645.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW31645.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW31645.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW31645.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971,
CC ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
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DR EMBL; KN847041; KIW31645.1; -; Genomic_DNA.
DR RefSeq; XP_016251861.1; XM_016389959.1.
DR AlphaFoldDB; A0A0D2CNN6; -.
DR STRING; 569365.A0A0D2CNN6; -.
DR GeneID; 27342456; -.
DR VEuPathDB; FungiDB:PV07_03262; -.
DR HOGENOM; CLU_010645_2_0_1; -.
DR OrthoDB; 3198922at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024708; Catalase_AS.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF26; CATALASE 2; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00438; CATALASE_2; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
FT DOMAIN 7..396
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT ACT_SITE 57
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 130
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 341
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 522 AA; 58449 MW; 5954BF61CE7B19AB CRC64;
MSEPHYTLAE GVPLPRNDII EQLSTGSGGG YVLLTSTQLL ENLAHFSRER IPERTVHAKA
AGARGHFEVT DDVSDVTDAD FLNGIGKKTE VLMRISTVGP ARGSADTVRD FRGFAIKFKT
NEGNQDWVFN NQPVFFVRDP MKFPSLNRSH KPHPRTNASD ASMFWDFHVN NQESIHALMF
LFGDRGLPSS VRHVNGYSGN TYKFTKDNGA SYVYTRITFK TVQGIHYYTN AEGADIAGKD
PDAHLLDLQN AIDKGDFPQW DVYIQVIRPE EVAAAPINIF DMTKVWPKGR YPLRKMGRVT
LDTNPLNWFA EIEQAAFSPS NMVPGIAASP DPMLQARMFA YPDAARYRLG VNYQFLPTNA
ARGPVYCPIE RDGFMNFTTN YGADPNYLGT RLKPVRFSNR TSAAAVASTD FATVQELKRL
SLGSADEVQL AHPVAAFTQV DDHRDFEQAT ALWKIMEKQE GAQARFVDNV AAHVSGVGEK
WLREAAYAMF AKVDKQLSEK IQKVTETKIQ NDHKHPHKSA WH
//
