ID A0A0D2DBY2_9EURO Unreviewed; 1049 AA.
AC A0A0D2DBY2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Fumarylacetoacetase-like C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV07_00100 {ECO:0000313|EMBL:KIW33234.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW33234.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW33234.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW33234.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR EMBL; KN847040; KIW33234.1; -; Genomic_DNA.
DR RefSeq; XP_016253450.1; XM_016386522.1.
DR AlphaFoldDB; A0A0D2DBY2; -.
DR STRING; 569365.A0A0D2DBY2; -.
DR GeneID; 27339294; -.
DR VEuPathDB; FungiDB:PV07_00100; -.
DR HOGENOM; CLU_009826_0_0_1; -.
DR OrthoDB; 1430490at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01299; Met_dep_hydrolase_A; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF115; FUMARYLACETOACETATE HYDROLASE; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF56529; FAH; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466}.
FT DOMAIN 107..449
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT DOMAIN 545..756
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
FT DOMAIN 805..1037
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
SQ SEQUENCE 1049 AA; 113489 MW; A1C6C8FF0869614D CRC64;
MAPGLLANGW HDDVALPPES TQTRYPYENL AFDPKLQPKR YEIAGTSPSS KILFLGVNIL
DSTGKEPYRG DVYIEGERIV AVGSVPRVEH LQAQPDVRVI QGRGRTLMSG LGDSHTHLTW
NNNALELLGD VSVEEHVLIT VKSALCYLDS GYTMCYGAAS AKDRLDCVVR DAINRGDIPG
PRYLANGREI ARRDGELAAG ITAFADGPLE MREVIRHHAR IGVDQIKLSM SGESITETRS
AEECFFADEE TAALQAHRNG LRVCSHARAR DSVIQCVKHG VDVIYHASYT DDVGMNMLTK
ARHKHVVAPA INWLYTTVHE AEPFGYTFEK AEQVGYKKEL EVAITALKEM NKRGITVLPG
GDYGFAWCPH GTYARDLEHF VKLLDFTPME SIIAATAGVA KLFMQEGELG KILPGYYADC
ILVNGDPLQD IAVLQNHDKL DVIMINGRIH KSSPADFVVV QPAAPSPQPK NPHNFVTFED
DLGRARVGHL DLETSLVHTL AMPSGSPLSN LQQVIELGHD TIVQTGDSFP LSSVKLLAPI
TDRDIVCVGN NYADHVKEYR ESGYDVQKIQ QKASFPTIFT KRSTSVIAAN EDIYAHPGFT
GCLDYEGEVG VIIGKPGFGI SEKDAMEHVW GYTIINDVTA REKQRDHGQF LMGKSPDTFC
PMGPIAVPKD SLPETLHVQT FVNGEKRQDG TTADLITSIP QLIEVISAGL TLQAGDVIAT
GTPAGVGVGF HPPKFLRPGD LVEVSVTGLG KLSNRVSDKR PNALARQPGS RLPVYNLERT
WGAAGLTRVG DKMVNVREIG SGSDTVVFVH GLGASSEYYA PLIQEAGLDA SRRLILYDLE
GHGLTPTAAS SVVSVESYVA DLEHLFSAKD ITRATVVGWS LGGLIAMLFA ERHASAVEKL
VLLGPGPNPF PEGAVKVFSD RAASVRAKGM DASGVAQAVA SAATSPRTQR QSPVLVSAVR
QSLLATHPEG YAKGCTALAK SKDTTIRIER LDVPALLIAG RDDKISPPAL ADTYARRLPN
AKLEVLEGVG HWHVIEDVGA VARALRGFL
//
