ID A0A0D2DN53_9EURO Unreviewed; 755 AA.
AC A0A0D2DN53;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=PV04_08713 {ECO:0000313|EMBL:KIW63732.1};
OS Phialophora macrospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW63732.1, ECO:0000313|Proteomes:UP000054266};
RN [1] {ECO:0000313|EMBL:KIW63732.1, ECO:0000313|Proteomes:UP000054266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW63732.1,
RC ECO:0000313|Proteomes:UP000054266};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR EMBL; KN846961; KIW63732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2DN53; -.
DR STRING; 5601.A0A0D2DN53; -.
DR HOGENOM; CLU_004131_2_0_1; -.
DR OrthoDB; 5475669at2759; -.
DR Proteomes; UP000054266; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 247..366
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 83929 MW; 6AADE7FEE94206E8 CRC64;
MDDTMDVDPE APRGVKRTAE EAGLPPEAPR RIKALDQDVV NKIAAGEIIV APMHALKELL
ENSIDAGSTS IEILVKDGGL KLLQITDNGH GIERDDLPIL CERFTTSKLK NFEDLMSIGT
YGFRGEALAS ISHIAHLRVT TRTANSSCAW QAHYQDGKLI PAKPGQTAEP KAAAGRPGTQ
ITVEDLFYNI PNRRRAFRSP SEEYAKVLDV ITRYAVHREG VAFSIKKHGE TGAGFSVAAA
TTKVDRIKQA YGGSVAKELM SFSTADPRWG FEASGYATNA NYSAKRTMLL LFINNRSVES
SAVKKAIEQT YQLFLPKGGH PFVYLSLEIA PNRVDVNVHP TKREVHFLNE DEIIELVCAN
IRESLAKVDT SRSFKAQTLL PGVLPMTPMN QRVAPGDATP PTDDSAPRRP STTKKPYENN
LIRTDSKMRK ITSMLPPALT TSTSQDDTPA TNGIQYTTTD REQIQVRLTS VKNLRAQVRE
SMHSGLTEVF ASLTYVGVID STRRLAAIQS GVKLYLVDYG MTCNEFFYQV GLTDFGNFGL
VQLQPAPDLR ELLDIAAEYQ LETDPSCTGL DKDQIVDKVF NQLMKSKAML AEYFFLNISD
DGQLETIPLL IKGYMPCMAK LPTFLLRLGP FVDWTDEETC FRTFLRELAS FYVPEMLPPP
QPKLDKGKGK AGDEEMMEPE LETQTQSQDA QDDAENSEAG PDNEETERRR KEIEHALEHV
LFPAFRSRIV ATQDMLNGVV EVANLKGLYR VFERC
//
