ID   A0A0D2DQ62_9EURO        Unreviewed;       485 AA.
AC   A0A0D2DQ62;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Guanine deaminase {ECO:0000256|ARBA:ARBA00014514};
GN   ORFNames=Z517_06526 {ECO:0000313|EMBL:KIW79911.1};
OS   Fonsecaea pedrosoi CBS 271.37.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX   NCBI_TaxID=1442368 {ECO:0000313|EMBL:KIW79911.1, ECO:0000313|Proteomes:UP000053029};
RN   [1] {ECO:0000313|EMBL:KIW79911.1, ECO:0000313|Proteomes:UP000053029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 271.37 {ECO:0000313|EMBL:KIW79911.1,
RC   ECO:0000313|Proteomes:UP000053029};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Fonsecaea pedrosoi CBS 271.37.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR   EMBL; KN846972; KIW79911.1; -; Genomic_DNA.
DR   RefSeq; XP_013283719.1; XM_013428265.1.
DR   AlphaFoldDB; A0A0D2DQ62; -.
DR   STRING; 1442368.A0A0D2DQ62; -.
DR   GeneID; 25306016; -.
DR   VEuPathDB; FungiDB:Z517_06526; -.
DR   HOGENOM; CLU_012358_0_1_1; -.
DR   OrthoDB; 65153at2759; -.
DR   Proteomes; UP000053029; Unassembled WGS sequence.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11271; GUANINE DEAMINASE; 1.
DR   PANTHER; PTHR11271:SF6; GUANINE DEAMINASE; 1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053029}.
FT   DOMAIN          77..476
FT                   /note="Amidohydrolase-related"
FT                   /evidence="ECO:0000259|Pfam:PF01979"
SQ   SEQUENCE   485 AA;  53289 MW;  83C8E3A2A0750410 CRC64;
     MEGPFAYYGT LIHSRTTSDI EILTDTLIIV DDTGKISHIY PQFEPENGRS LEDSIGSLLN
     RPDAQLPVVR LESPSQFLVP SFIDTHVHAP QFSMRGLGQG LHILEWLDQI TFPHEAKFCD
     TDYARQVYSR CVEMGLRQGV TTACYFGSLH TPATKILVDV CLEKGQRAFV GKTCMDNPDT
     NPAYYREDTA DAVAGTQEVI RHCRAVDEKG DMVRPILTPR FAISCTSESL TELGKLAKEH
     EHTYGVGQGV PNQTHFCEAQ QEIDATLNQY KGFTCEADLY AHYGLFDHNS VLAHCTLLSE
     ADQAKIKQQG CGIAHCPASN TTVGGGFMAA LIRKLLSDGV TKIGLGTDSG GGFSCSIMDA
     MRLAVIVGNA REMISGGKEE RLKLDEIFYM ATLGGARVLR MEDRVGSFEV GKQFDALLVD
     MSDPPPHHGE SGFPGGIQTM MDGESRTAQG IRQVWEKWVM TGDDRNLTKV WVGGRTKKDI
     THGKS
//