ID   A0A0D2DQA2_9EURO        Unreviewed;       863 AA.
AC   A0A0D2DQA2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN   ORFNames=PV06_09965 {ECO:0000313|EMBL:KIW37989.1};
OS   Exophiala oligosperma.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW37989.1, ECO:0000313|Proteomes:UP000053342};
RN   [1] {ECO:0000313|EMBL:KIW37989.1, ECO:0000313|Proteomes:UP000053342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW37989.1,
RC   ECO:0000313|Proteomes:UP000053342};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN847342; KIW37989.1; -; Genomic_DNA.
DR   RefSeq; XP_016258205.1; XM_016411451.1.
DR   AlphaFoldDB; A0A0D2DQA2; -.
DR   GeneID; 27362039; -.
DR   VEuPathDB; FungiDB:PV06_09965; -.
DR   OrthoDB; 276651at2759; -.
DR   Proteomes; UP000053342; Unassembled WGS sequence.
DR   GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR004199; B-gal_small/dom_5.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR023230; Glyco_hydro_2_CS.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032312; LacZ_4.
DR   PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR46323:SF1; LACTASE; 1.
DR   Pfam; PF02929; Bgal_small_N; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF16353; LacZ_4; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SMART; SM01038; Bgal_small_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053342}.
FT   DOMAIN          575..859
FT                   /note="Beta galactosidase small chain/"
FT                   /evidence="ECO:0000259|SMART:SM01038"
SQ   SEQUENCE   863 AA;  97195 MW;  5CC948EC4C8F548C CRC64;
     MGWLTWLTGI YRDVYLLAYP DLARIEDFFI KTDLDDDYAD AELIVELDLS LRLTCDLKIT
     LCSPNQDSKI FSDQVALESH DTRWQKNYPV KAPLKWTAET PVLYHVELGL SSKGRSLQKI
     QHRIGFRKVE IKKGLLTVNG APILLRVVNR HEHHPDFGRA VPVDFLREDL VLMKRHNINA
     MRCSHYPSQP ALYSLCDELG LWVLDEADLE CHGFNDAVAR SLSGAEGMDY AQRKALTFDH
     AASFTSDNKD WETAYIDRMT QLVQRDKNFT CVIIWSLGNE SFYGRNHKAM YQYAKRVDPS
     RPVHYEGDSK AITTDMYSYM YTSVPDLVSL AREEGVSPDG SYEKPIILCE YGHAMGNGPG
     LLEDYQAAFR EHERLQGGFI WEWANHGLRK ASDEVEGKDI FAYGGDFGDV PNDGTFVMDG
     LCYSNHTPTP GLTELKKAIA PIRAWFEPNS DKITVENRFN FKTLEGFAAH YEVEALADTR
     ELLTSGLLDI PSVNPGSAST IALPKEVLQY RGYAKAECWL TVMFTLKDNC AWADSGHEVT
     FVQHQLNIKH PLFDKPVIAP KPQPLDVSST RQYLSIAGPD FSVSFDKIHG LIKSWTFRGT
     PLLHEPEWPV GPIQLGFWRA PTDNDAAWQT ERWKHWGLNS LTTQLRAFDV YHPSVDETQV
     KATTYVGPPI LAWGFHVETT YRIGATGTIS IRVHVKPVGS APKNLPRAGW DFQLSKVFEH
     ARWFGLGPGE SYHDKKSAQR VGVFDASIPA LHTPYEVPQE NGNHVDTRWV EVLDGRGMGM
     KITLSGAKRN PATFHFAVSE YPAAELERAK HGPELVKGDA IYLRVDRDVS GVGTGACGPA
     IKEQDLVRCE EMEFEVSLEP VLP
//