ID A0A0D2DWL6_9EURO Unreviewed; 730 AA.
AC A0A0D2DWL6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=High osmolarity signaling protein SHO1 {ECO:0000256|ARBA:ARBA00017350};
DE AltName: Full=High osmolarity signaling protein sho1 {ECO:0000256|ARBA:ARBA00016255};
DE AltName: Full=Osmosensor SHO1 {ECO:0000256|ARBA:ARBA00029697, ECO:0000256|ARBA:ARBA00030785};
GN ORFNames=PV06_08484 {ECO:0000313|EMBL:KIW39914.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW39914.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW39914.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW39914.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847339; KIW39914.1; -; Genomic_DNA.
DR RefSeq; XP_016260130.1; XM_016409822.1.
DR AlphaFoldDB; A0A0D2DWL6; -.
DR STRING; 215243.A0A0D2DWL6; -.
DR GeneID; 27360558; -.
DR VEuPathDB; FungiDB:PV06_08484; -.
DR HOGENOM; CLU_015390_1_0_1; -.
DR OrthoDB; 4260488at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:UniProt.
DR CDD; cd20824; C1_SpBZZ1-like; 1.
DR CDD; cd11912; SH3_Bzz1_1; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035459; Bzz1_SH3_1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR020454; DAG/PE-bd.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00008; DAGPEDOMAIN.
DR SMART; SM00109; C1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU01077}; Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 7..274
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 404..454
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 567..627
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 672..730
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 479..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 152..199
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 481..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 80722 MW; 8D15C3395E8F4E09 CRC64;
MAHVATVSFG AELKDGYKAV DNWVGLGINW LTEIQEFYQE RSAIEKEYSQ KLTALAKKYY
DKKSKRSSNL SVGDNPALTP GSLEAASLTT WTTQLSTLEA RANEHGKFAQ DLISQVATPL
EYNARKLEEL RKSHGEYNNK LIKERDSSYG ELKKLKTKYD SVCQEVENRR RKAESGFDKA
KAQNAYNQQI MEMNNVKNTY LIGIHVTNKL KECYYHEYVP ELLDSLQDLN ETRVSKLNSL
WLVATTLETN TLKRSIDHLS HLASEIPRNN PSLDSNMFVR HNAVQWQEPS DMAFEPSPVW
LDSDNMMTDE TSKIFLRNIL QKSKPLVSQL KTDSAQKRRD LENVKKARQN IREGKDKRDE
VLCVVSQFNV QEELHAIDRK RLTAEVETST ITSVVGDLSM YGKSHAFKSE TFKIPTNCDL
CGDRIWGLSA KGFICTDCGF TCHSKCQMKV PADCPGEQTK EEKKKLKIER QAAASVAVEA
PVPNGQNSAP TLTRQDTMSS LSSGYAASAT RSVSGTIPRS TGEELSSPLT TITSSSASTS
GARRNRIVAP PPTTYVSAPS DSALNGSGQK RGKMLYAYEA RDDGEISLPE GTEFKIVEPD
DGGWTKVHAG MGKEGLVPTA YLEELPTPAS TPAQERPPSL YSNSSASLAS SNMASAGRKK
QGPAVAPKRG AKKVKYVEAL YPYTAQSDAE FDMAEGEKFI LISMGGGDGW ADVEKNGETR
SVPANYIQEI
//
