ID A0A0D2DWM2_9EURO Unreviewed; 664 AA.
AC A0A0D2DWM2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=UmuC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV06_00167 {ECO:0000313|EMBL:KIW47473.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW47473.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW47473.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW47473.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KN847332; KIW47473.1; -; Genomic_DNA.
DR RefSeq; XP_016267689.1; XM_016400636.1.
DR AlphaFoldDB; A0A0D2DWM2; -.
DR STRING; 215243.A0A0D2DWM2; -.
DR GeneID; 27352241; -.
DR VEuPathDB; FungiDB:PV06_00167; -.
DR HOGENOM; CLU_012348_7_1_1; -.
DR OrthoDB; 118267at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR041298; UBZ3.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45873; DNA POLYMERASE ETA; 1.
DR PANTHER; PTHR45873:SF1; DNA POLYMERASE ETA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR Pfam; PF18439; zf_UBZ; 1.
DR PIRSF; PIRSF036603; DPol_eta; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
DR PROSITE; PS51907; ZF_UBZ3; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 43..305
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT DOMAIN 582..616
FT /note="UBZ3-type"
FT /evidence="ECO:0000259|PROSITE:PS51907"
FT REGION 613..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 73955 MW; C4628768C70C0CC1 CRC64;
MSSSQPFQPS SPLAGGKRRK SRFTYKHLHL LGQSSTTCPL RVIALIDYDA FYAQCEMVRL
GVVESQPLAV QQWQGLIAIN YPAREYGLSR HVPITEAKAK CPEIVIQHVA TWREGDTKWA
YRDDAASHIQ TDKVSLDPYR LESRKSLALV KEILPPPPIQ KVEKASIDEV FLDLSAQIHQ
ILLERYPELK YAPYDDPTEH LPLPPSTALD WQADALVDLD SAETEDDDPD WDDVAMNIGS
EIVRGVRATI RERLKYTCSA GVARNKMMAK LGAGYRKPNQ QTIVRNRAVQ HFLSGYKFTK
IRNLGGKLGD QVVDTFNTDE VTELLKIPLE QLKSKMGEET GTWLYGTIRG EDHSEVSSRT
QIKSMLSAKS FRPSINTTDQ ANKWLRIFVA DIYARLVEEG VLENKRRPKT ITLHHRQGGQ
TKSKQLPIPS GKKIDETILF ELAKTLLGQV VVDGRAWPCA NLSLSVGGFE EGVAGNKGID
MFLLKGEEAK AAIEAPSRSN TTTPNIEDLI PAKRRRLNDA PTNIARFFAK GESTEEASES
ADEDIVAQEH HLEANNDGNG NGDEVYHDEG PDQHLTHAMQ ERDIATYFCQ ECQKSINEPD
RGEHEDWHFA KQLQAQDAPA VTGPSNSRPP GPLHTNKTKR GGTGSNSRGR GSKPEKGQSR
LAFG
//
