ID A0A0D2EKG3_9EURO Unreviewed; 374 AA.
AC A0A0D2EKG3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE RecName: Full=Pre-mRNA-splicing factor 18 {ECO:0000256|ARBA:ARBA00018242};
GN ORFNames=PV05_07460 {ECO:0000313|EMBL:KIW55155.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW55155.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW55155.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW55155.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PRP18 family.
CC {ECO:0000256|ARBA:ARBA00008137}.
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DR EMBL; KN847320; KIW55155.1; -; Genomic_DNA.
DR RefSeq; XP_013315739.1; XM_013460285.1.
DR AlphaFoldDB; A0A0D2EKG3; -.
DR STRING; 348802.A0A0D2EKG3; -.
DR GeneID; 25329368; -.
DR HOGENOM; CLU_039675_1_0_1; -.
DR OrthoDB; 199348at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR InterPro; IPR004098; Prp18.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR039979; PRPF18.
DR PANTHER; PTHR13007; PRE-MRNA SPLICING FACTOR-RELATED; 1.
DR PANTHER; PTHR13007:SF19; PRE-MRNA-SPLICING FACTOR 18; 1.
DR Pfam; PF02840; Prp18; 1.
DR Pfam; PF08799; PRP4; 1.
DR SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR SUPFAM; SSF158230; PRP4-like; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 145..172
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|Pfam:PF08799"
FT DOMAIN 222..365
FT /note="Prp18"
FT /evidence="ECO:0000259|Pfam:PF02840"
FT REGION 1..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 42483 MW; 7B6C276A893872E0 CRC64;
MDFKSLMASQ IAKSKPKPSP SPSQSQSPDP STPSATQKYL RRAELEAARE AAYAAEQARI
DAEREERASK KRKLEEEEAE RAAVREEKKR RLAEESRKRR LEEEREEERK RRKRLGLPDL
PDPAIEEGNK SSSTSLEDIP DDELRSKLRS LNEPAALYDE SHASRLKRYH ALTAPKSLKP
KLSDGPIPTT LEPVPEKDML LPSTLPAENT PEHAFLYRQL ASYFTLLLRE WSFALSQRDA
AVKASTSGKA AHNSYLQVLK DLTPLFRRFE RADLEHNLLD PICQIVRSAQ ARRYVEANDK
YLTLSIGKAA WPIGVTMVGI HERSAREKLS ESGEGKQAHI MTDEVTRKYL QSIKRCLSFA
QTRWPPEDLG QLMG
//
