ID A0A0D2EV05_9EURO Unreviewed; 590 AA.
AC A0A0D2EV05;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=Purine permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=Z517_07890 {ECO:0000313|EMBL:KIW78057.1};
OS Fonsecaea pedrosoi CBS 271.37.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442368 {ECO:0000313|EMBL:KIW78057.1, ECO:0000313|Proteomes:UP000053029};
RN [1] {ECO:0000313|EMBL:KIW78057.1, ECO:0000313|Proteomes:UP000053029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 271.37 {ECO:0000313|EMBL:KIW78057.1,
RC ECO:0000313|Proteomes:UP000053029};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea pedrosoi CBS 271.37.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; KN846973; KIW78057.1; -; Genomic_DNA.
DR RefSeq; XP_013281865.1; XM_013426411.1.
DR AlphaFoldDB; A0A0D2EV05; -.
DR STRING; 1442368.A0A0D2EV05; -.
DR GeneID; 25307380; -.
DR VEuPathDB; FungiDB:Z517_07890; -.
DR HOGENOM; CLU_017959_7_0_1; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000053029; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053029};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 550..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 63008 MW; 7C395473D363D272 CRC64;
MGAGDRIGPD MGPKKTLADR MNSLRKTFFT KHGLIGEYDY AFLFRPNIPF LKKPRRAAPF
FGLHDSMPIV LAFLLGFQHA LAMLAGIMTP PIILSGQGGV NLPADYQQYL VSTSLIVCGI
LSSIQITRFH IWRTPYYIGT GLISVVGTSF AIIPVATGAF AQMYANGKCQ LDAEGNRLPC
PDAYGALIGT CALCALVEIA LSFLPPKALR RIFPPIVTGP TVILIGVHLI ETGFMNWAGG
SGLCASRPEE GPFALCPSVG APHALPWGSA EFIGLGFLVF VTILLCERFG SPIMKSTSVI
LGLLMGCIVA AACGYFDDSG ITAAPVGSFV WVKTFKLSLY GPIVLPVMVV FIICACEAIG
DVTATCDVSR LEVEGPIFES RIQGGVLADG LNGCLAALMT ITPMSTFAQN NGVIALTRCA
NRKAGYFCCF FLIVAGIFAK FSAALVAIPS PVLGGMTTFL FCAVAVSGMA IVNRVPFNRR
TRFILTAALA LGYGATLVPT WFAYVFTYDG DNRSLRGFYD AIELVCETGF AITALVAMLL
NLTLPEELED LPAEEETKEV EEEGRSDAAG SVDEGVHKKV NVEMPSKEVV
//
