ID A0A0D2EVU6_9EURO Unreviewed; 607 AA.
AC A0A0D2EVU6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=FHA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV05_00114 {ECO:0000313|EMBL:KIW59848.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW59848.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW59848.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW59848.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847317; KIW59848.1; -; Genomic_DNA.
DR RefSeq; XP_013320432.1; XM_013464978.1.
DR AlphaFoldDB; A0A0D2EVU6; -.
DR STRING; 348802.A0A0D2EVU6; -.
DR GeneID; 25322022; -.
DR HOGENOM; CLU_017542_0_1_1; -.
DR OrthoDB; 463769at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProt.
DR GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR CDD; cd16458; RING-H2_Dmap-like; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR042823; Dma1/Dma2_RING-H2.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15067; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR PANTHER; PTHR15067:SF8; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF17123; zf-RING_11; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 223..286
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 363..410
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..554
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 65935 MW; EEA7308683ECCA10 CRC64;
MISSPTPVTS GGTAGTGLDL TRTSSRRRGL SYLRALSHSR SSGQTSPNEP SRSPRHYFQR
SLSYNDNRPD ASASGRRRSA SRPNEPTSQL ATEPPQIHSS PQNPRPSSPP TGQSIPIRTA
TIPGPAPVTI EEQNTDDMAR HRSSTGRRHT SSHQQADTPM VDSPASRPAN ATTVSKAKEG
HEGESKPQLP TIRLFPHQEV RNGRPSLTFT PISRTLPSEH SIIRVGRYSE REGVPSANPN
TPSDAPVGFK SKVVSRKHCE FCFVDGQWQI KDVASSSGTF LNHIRLSQPN TESRLFPIKD
GDIIQLGIDF RGGEEMIFRC VKIRIECNRA WQKKPNNFNK SRHQQLQSLA RDQPSADSNS
GECSICLGSV LPCQALFVAP CAHVWHYKCI RPLLEGRNST YPQFQCPNCR AYFDLTADVD
IAQSDIDEWM ENSDDRENAP TNANGDAGND ASTSPDHEVN EADTTDSGAT HETPDTSEDS
GDHPTVTVSD PIDVPNNGGS ASTPRTSGLL ARRQAANPAS PEVNSINGNI DMPERPDEDE
VHTHLEHQRT RTQTPDPEHI IAGEGPLTPR NNAGPFVFDG SAGRSDAGQL AVPGIPEVTN
GNNPASL
//
