ID A0A0D2EWX7_9EURO Unreviewed; 1516 AA.
AC A0A0D2EWX7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=PV05_07970 {ECO:0000313|EMBL:KIW52324.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW52324.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW52324.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW52324.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; KN847321; KIW52324.1; -; Genomic_DNA.
DR RefSeq; XP_013312910.1; XM_013457456.1.
DR STRING; 348802.A0A0D2EWX7; -.
DR GeneID; 25329878; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241:SF620; ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE PDR18-RELATED; 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 579..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 747..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1174..1193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1205..1224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1244..1274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1286..1309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1316..1334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1441..1459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..393
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 832..1075
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1516 AA; 169393 MW; DD5FF0B095B55EFB CRC64;
MASSLEGQRG PESDNNHAAE SRCQEDSRES HTSSESHMSE ELQTSESMSS RSDYEAIEAT
DRAELTRVAS EVKRGEVHDP ALDPYSPTFD VYKWTKVVMH AAEDANIKLR RASITFKNLD
ISGSGIAMNL QPTVASYLLG AFRLHEWLRL AKKPQRKILT GFEGHVKPGE TLLVLGRPGS
GCSTLLKTLA GELRGLKLGH DSVIHYSGIP QHEMIKSFKG EIAYNAEVDQ HFPHLTVRQT
LEFAAAMRTP ANPILGTSRT EHVQRMTAVA MAVCGLTHVR NTKVGSAYVR GASGGERKRV
SIAEMMLSFS PIGCWDNSTR GLDASSALSF VRTLRLSADI TGSAHAVAAY QASQAMYDVF
DKVVVLYEGR EIYFGPTTFA RNYFQDMGWL CPPRQTTPDF LTSVTNVQER RPRPGFEAKV
PRTPIEFEGH WRGSELRRLL QQDIMNHEEE VSSSSAADEF KAARRAVQAH HVPPSSPYTV
SIPMQIQICT KRGFQRLWNE KVIRLTLVIG QGSMALIIGS AFYGMIDDTN SFFAKGSVIF
NAVLLNALVA VTEINRLYDQ RPIVEKQVSY AFYHPFTEAL ATVIADLPVQ VLTAVVFNII
LYFLGGLRKE AAQFFIFFLF AFLTRLAMTG LFRTIGAATK TISQALAIAA VLVLAIVIYT
GFTIPRPNMH PWLKWVSWCN PVAYSFEALI VNEFHGRQFP CGSYIPAYPD RLGDTFICSV
PGSIVGQTTV SGDRYLETSF QYRYDHLWRN LGIIIGFLGF FMFSYLGVTE INSKPSGKGE
VLLFRHGHVP RYIEDGLKHA DQASPGAPVA IAERRQSQDE DIQAIPPQKA VFTWRDVTYD
IPVEDGTRRL LEQVSGWVKP GTLTALMGIS GAGKTTLLDT LAQRTSIGVV SGDIFVNGKP
LDSSFQRKTG YVQQQDLHLE TSTVREALRF SAMLRQPRSV SKKEKYDYVE EVIKMLNMED
FAEAVVGVLG EGLNVEQRKL LTIGVELAAK PTLLFFLDEP TSGLDSQSSW SILSFLRKLA
DHGQAVLSTI HQPSAMLFQE FDRLLFLTNG GRTVYFGDIG PNSQTLISYF EGHGARHCTD
SENVAEYILE IVNPETSAQA NRDWVEIWRS SEENKTMLAE LDRINRETNA SGTRAGAEQD
ADKDQSQFAM PLYTQTYYTT TRAFQQYWRT PGYVWHKLAL GVASALFIGF SFWQSDSSQQ
GLQNVLFSVF MLTAMFTALI QQIIPRFVIQ RSLYEVRERP SKAYSYVAFL LANVIVEIPY
QILLGIMVYA SYFYSVFGIQ SSERQGLVLL FCIQIFVYAS TFSQMIIAAL PDAETAGIIS
TLMFAMCVIF NGVLQPPDAL PGFWIFMYRV SPFTYIIDGI VATALHGRRV VCAAHELSIF
NPPPNTTCGQ YLAPYLRQAP GTLYNANATA KCEYCALSLA DQYLSPRGIS WSLRWRNFGL
LWAYIAFDLA MIPLLYYTFR MRKWGGKLGA GAGKRRRGLN VAYAWARAAG KQSRTLVTGR
REKLPLDKRA ENARVY
//
