ID A0A0D2EXX9_9EURO Unreviewed; 637 AA.
AC A0A0D2EXX9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Glycoside hydrolase family 2 protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV05_00775 {ECO:0000313|EMBL:KIW60568.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW60568.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW60568.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW60568.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; KN847317; KIW60568.1; -; Genomic_DNA.
DR RefSeq; XP_013321152.1; XM_013465698.1.
DR AlphaFoldDB; A0A0D2EXX9; -.
DR STRING; 348802.A0A0D2EXX9; -.
DR GeneID; 25322683; -.
DR HOGENOM; CLU_009935_2_1_1; -.
DR OrthoDB; 2063192at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 608..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..162
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 289..325
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 365..494
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 637 AA; 71333 MW; 2640AC34D4948600 CRC64;
MTASFAYPRP DFQRKALSWT SLNGSWDFIF DDTDVGLSEL WQRTGIPVHT GGHDKRAVQV
PYAFQTPASG IGIHEAHEVI WYERTICDIR PKHEIAQGYR VLLRFGAVDY ECSVWADGRW
IGGHRGGHVP FDLDVTDAFL SDTTEGTVRL TLRVRDSPYD LSQPRGKQYW GPVSADIFYS
PTSGIWLSVW LESVPVMRLG SSSEGTILRS NDIESGQLHA RVAVLGRHRG GRCAVEIEAS
LEGIPVGKTR RDLPKDKDFV GLELGLHVPN AAELQKTAPF NIDGSWLNGV ALWHPEHPIL
YDVTLRLYDA IGTLVDEVQT ATGMRSLSWQ TGDGTFRLNG KPYFQALVLD QGYWKETGMT
PPSPDALKAD IEMSKKMGFN GCRKHQKVED PIFLYWADRL GYLVWAEMAN AYEFAEEYVE
RFNAEWMEAV KRDINHACIV TWTPVNESWG YPSLKNSIEQ RDHIRSLYYM TKALDPTRPI
NDNCGWEHVQ TDLTTYHDYA DSPELSLSCS RMEGGILDKK SNREMFTQPI YAGSILLDAG
AQHQAGAPVI CTEFGGVNIA AAQNETAGEK DWGYTTAADS RDLLRRLEKL VMAVVKGGHS
CGFVYTQLWV PFAPLPFLSL GTIVAATMVL PLTLKQM
//
