ID A0A0D2F6H8_9EURO Unreviewed; 616 AA.
AC A0A0D2F6H8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 13-SEP-2023, entry version 25.
DE RecName: Full=Purine permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV05_04280 {ECO:0000313|EMBL:KIW55549.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW55549.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW55549.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW55549.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; KN847319; KIW55549.1; -; Genomic_DNA.
DR RefSeq; XP_013316133.1; XM_013460679.1.
DR AlphaFoldDB; A0A0D2F6H8; -.
DR STRING; 348802.A0A0D2F6H8; -.
DR GeneID; 25326188; -.
DR HOGENOM; CLU_017959_7_0_1; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 582..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 66195 MW; 874F539BCFBDD648 CRC64;
MEPDRIGPDT TPRRPFVDRV KDVPRRVIRS LTTKEGLVGD YDYAFLFTPK LPFMKKQTQT
APFFGLNDKM PILLALLLGF QHALSMLAGL ITPPIILSGT GGANLPTETA QYLVSTSLIV
CGILSSIQIT RFHLYKTPYF IGTGIISVVG TSFATIPVAL GGLSQMYASG YCPTDADGNR
LACPKGYGAI LGTACICALL EICLSFAPAK VLKRAFPPLV TGPTVVLIGI NLISSGFENW
AGGSGSCRAR PEEGIYQNCP TNFAPHPLPW GSAEFIGLGF SVFITIILCE RFGSPIMKSC
AVVIGLLVGC IIAAATNYFD DSGIKSAKAA SFIWVETFPL SLYGPMVLPF LAVFLVLMME
AIGDITASCD VSRLEVDGPL FDSRIQGGVL ADGLNGMLAC LCTITPMSTF AQNNGVIALT
RCANRKAGYC CCLWLILMGI FAKFAAALVA IPSSVLGGMT TFLFSAVAIS GVRIISTVPF
TRRNRFILTA AMSVGFGATL VPDWFDYVFT YEGDNSALRG FMSAIELVME TGFAVTAFLS
LFLNLAIPEE ADDDAVETTA NTVDADDNKE WERIRRRSQL KDMRNSEDLT RGSTDIEVSG
GIQQGEVDKM RTIKDG
//
