ID A0A0D2FNP3_9EURO Unreviewed; 1630 AA.
AC A0A0D2FNP3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=CCR4-NOT core complex subunit Not4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Z518_07250 {ECO:0000313|EMBL:KIX03697.1};
OS Rhinocladiella mackenziei CBS 650.93.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Rhinocladiella.
OX NCBI_TaxID=1442369 {ECO:0000313|EMBL:KIX03697.1, ECO:0000313|Proteomes:UP000053617};
RN [1] {ECO:0000313|EMBL:KIX03697.1, ECO:0000313|Proteomes:UP000053617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 650.93 {ECO:0000313|EMBL:KIX03697.1,
RC ECO:0000313|Proteomes:UP000053617};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Rhinocladiella mackenzie CBS 650.93.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847479; KIX03697.1; -; Genomic_DNA.
DR RefSeq; XP_013270833.1; XM_013415379.1.
DR STRING; 1442369.A0A0D2FNP3; -.
DR GeneID; 25295321; -.
DR VEuPathDB; FungiDB:Z518_07250; -.
DR HOGENOM; CLU_001793_0_0_1; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000053617; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Reference proteome {ECO:0000313|Proteomes:UP000053617};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 16..60
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 202..229
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 202..229
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 230..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 831..1221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1431..1465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1499..1581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 80..108
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 422..449
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1585..1612
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 250..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..885
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..910
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..1031
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1059
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1525..1540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1551..1581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1630 AA; 176214 MW; D26FA69AA08CC314 CRC64;
MNRSQDTVID DDEETCPLCI EEFDLTDKNF RPCPCGYQIC QFCFNSLKNT YEKSTCPNCR
RPYDEKTIQY KIPTAEEFKL DQLNKNKKQA AAKRKETEKR EVENSARRNL AGVRVKQQNL
VYVIGLIPQI KDEQALLQTL RGPDYFGQYG EIEKIVVSKA KPGAANQGIG VYVTYARKED
AALCINTVDG SPNGDRVLRA QFGTTKYCSA YLRGETCNNK NCSFLHETGE DGQHSSLQNE
PHVTKIPPKP PMGSQSSHVS LPPRPQSTTQ STTTQHHTKE DDSSRKNSHD SSALPSTASW
ANASAPVARA RRASQANSRA TPSPQMIHAS LSSQKPDESK AKETTPAPQS STVSTKAVPP
TDTSASKPKS KPVDYVQQQY DAVLRGVSPN FRFVYDDSCL SPEVRAAVDD MPPLIDPYGG
AKRRAMRERD EAERAKVEAE AKAKLEAQAT SAAEDTLDDE NVVAGSLALG GEPEDDPRSS
SVRGAIGRPP QPLSDQFSSM NLNTHSLTPQ QRQQLALINT GNLQQAADLG QSAAQNTAFE
MSDFDRRGPQ YSQAQYEQIS SHQRHGSRYF NNDSKAASNA NRFQGQQQTF YSSGVQGPPP
GLPTAGTPPV SGGGMFAHGQ NFTNPGFGPS KDTNTEVYSR NRSGTNQGHD MSKRELLLSL
QNNPLRSPPL SAPAPGVLNP LYGQYQGTYQ DPGLVKQRKK GKKHRHANTS SSGGGVEHLA
DPSIVSTRVH QGNTTGQGLF GGNQVDEKNF PPLPIRSEIQ PTPIHSRVSS YHSFQSSGLR
SSTPKIPPGF ELIHGHPMPP SRQESPAQAS QVAGQRITST ACATVAPAVP LVPVGPRTSS
PKLKIPEITN EGTKNVGEDE NVSIHAGKQR NEVSDASYAS PSKEATRQKF ETDRKPDVLD
KSEENFAQKD EALLPSKSGD TESKGKAVAQ KPEKREPPPP GISANATAAP SAASAPTGGV
GKSGAPILDA AVVGTSGTLS SRPATPVTTT PSDTSKASMA RPRTLRVTTG MTTKTAEPTP
ASATTEKSGI LPPISVTKRG SRRPSLSSAQ HSRPSTPAMS ERFVSHDVSR ASSPPPNVVG
SAPERVKSKN QQKKDRRDKA KKTTEASEAG SASTPPTVEE VAPVIARQKK QKRRMESSPV
PIVDDKPKDK PADDVETPTS KPEEVIDKQT PEADSKKASS KTQEKERTLS ATNKTAKGPN
QAETLGTPPP ATPNKEPTSR GVDLLKAPYT LRDLYNEVGK VPSHAEKANL VQKLLDEHVS
AMPKIISSMI QSGDLSKDHP WLNPPNFNSA AYKLAPDARR GQEYLDGNGY SANDAFGYIY
LPLKEKQALK DGHAVSVADA GDRRDDLLKR CLVTPSGWVL RHLSADESEK ILELEERRQM
YMEEFGEVGT MDGLGVLEAD DFTNLGGGME RLGRQGEHHG VVWVTGDADQ MGEDDEFDAF
DDEDGEIDGE IGVSDEEPEL EHEGLDDDDD NAAAADAAAL DLQDSVNMPG AWDLLPSASH
SGTKSTGIGA GRVMSLPGLN PHSDLPSLRS PNTQSNVGNA PHAPLGHRHG SNTRAMSSKA
NMASSGQTQS QNFTTAPTNL RALDSETLQK RVQEKQRELE QARKEMDKIE KLWTKKSKDI
GRWREGLTKA
//
