ID A0A0D2FQP4_9EURO Unreviewed; 2303 AA.
AC A0A0D2FQP4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=THO complex subunit 2 {ECO:0000256|ARBA:ARBA00019596};
GN ORFNames=PV04_02903 {ECO:0000313|EMBL:KIW70658.1};
OS Phialophora macrospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW70658.1, ECO:0000313|Proteomes:UP000054266};
RN [1] {ECO:0000313|EMBL:KIW70658.1, ECO:0000313|Proteomes:UP000054266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW70658.1,
RC ECO:0000313|Proteomes:UP000054266};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the THOC2 family.
CC {ECO:0000256|ARBA:ARBA00007857}.
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DR EMBL; KN846957; KIW70658.1; -; Genomic_DNA.
DR STRING; 5601.A0A0D2FQP4; -.
DR HOGENOM; CLU_000511_1_0_1; -.
DR OrthoDB; 179356at2759; -.
DR Proteomes; UP000054266; Unassembled WGS sequence.
DR GO; GO:0000347; C:THO complex; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR InterPro; IPR040007; Tho2.
DR InterPro; IPR021418; THO_THOC2_C.
DR InterPro; IPR021726; THO_THOC2_N.
DR InterPro; IPR032302; THOC2_N.
DR PANTHER; PTHR21597:SF0; THO COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR21597; THO2 PROTEIN; 1.
DR Pfam; PF11262; Tho2; 1.
DR Pfam; PF11732; Thoc2; 1.
DR Pfam; PF16134; THOC2_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 127..848
FT /note="THO complex subunit 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16134"
FT DOMAIN 850..925
FT /note="THO complex subunitTHOC2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11732"
FT DOMAIN 1211..1514
FT /note="THO complex subunitTHOC2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11262"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1522..2303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1114..1132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1522..1536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1537..1568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1595..1637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1638..1654
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1678..1796
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1797..1821
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1844..1884
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1885..1910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1936..1952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1976..1992
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1996..2046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2047..2076
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2077..2125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2127..2145
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2155..2171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2176..2281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2303 AA; 255547 MW; D8ACB14DDB7B09CF CRC64;
MPPPVGGKRK RPERGYSDDQ PPSRPSPHRP QNLNLAQSGY QSNERDYTQS RGRGGRRSSR
GGRGANAVSS PINSASERPP TLTRTPVAEA EPVRVNGNMS AIQPTSLEAP VLSDPPSESQ
PYSYTYLTSE TCDSWQTGGR EDTLRQGLEG MQEEEGTQLI VLMQELVQSV VYGRLGPAEA
GDLVKQMLES EIQEDEEQSV PHPTALQAAL LDSVSVMFEN NPTIPLDRLS VFLFATGIPH
ELLRHEIDAA LLEKFNMIRN TFSRMGIRKQ TNLLYRQANF NLMREESEGF AKLMTELFTT
SSNEAPTADI VEETVEKVKA MIGAFDLDVG RSLDVVLDVF SAVLVKQCRF FVKFLRASPW
WPRSSVMARK TQVLTGLPLW ALPGSPEWHL TEEQKQLVAQ ETRTRDQAFW SDAREKGLQA
FYLLGGSRPA QENVERTSSG DELLAQWVHE TGTLPPPGNR DAAQLLGFKL RFYSSSPARD
EMDILPDNLI YLSALLIKIG FVSLKDLYPH IWRTDDAMDE LKQQKTKEKL ERERAARPGA
GVKNALASAG ALADDTLPVP SRLKESATRS NTPVREQDSE KPPTKESAPA DQKVLLLKSL
LAIGALPEAL FILGRFPWLM DLIPELPEYI HRILHHSLSK VYGDIQPLQK RPSLRAQKPS
YETDVPGVPK GQVKIVESAE RKVLRWAQLD KNDSLDGTDY RFYWDEWNDN IPVCQSVEDV
FTLSNIFLPL VGVKIGQDVG LLLKISRIGK HSLHTDKSES NRSRWLDLIK RTLLPSLSLT
RSNADAVNEV FELVSNFPVN IRYLMYLEWS SGRTSRNPDI KAAFDQARAE TKDILKRISN
TNVRPMARAL AKIAFANPHI VITTALTQIE VYDSIAEVFV EGARYFTDLG YDVLTWAIVS
SMAKTGRNRT QEGGIFASRW LSALSVFAGK IYKRYGMMKP GPILQYVAEQ LEHGNTMDLK
MLEQIVLSMA GIATDTSYND AQLQAMGGGP LLQGQIILQL LDRRHDSKRT SERLIKSLQD
TGLAARFLIS MAQQRQAVVF EDSEIPLKAI GNTYDEVHRV MVQYLDLLRT NLSPDEFRAT
IPDVVSLLVD YEIRPEIAFW IARPLISRQM QDYDRENRKE QQGEEVKDIN GDVDMSDQIN
GGSEEDGEAV ETENITNDSP ALGDTMGPAL DLDAISKTLS TADSIPEDCW HPVMKDLMTA
IEPSLPEEVT QIIGTGFYST FWQLSLYDIA VPSKSYEDES ARQRKRMAAV TADRSDVSVS
GTKKKEMATR EIQDLIDKLL LENKQHLKSF LEGKTRLQRE KEQWFLGKTR MDRALNTALM
EHCFLPRMLS SPLDAYFCFK FLKLLHSGGT PNFRTLGFYD LFFKTARLIS LIFMCTSKEA
DNFGKFLNEV LKDLGRWHGS KSTYEREGCG GLKRNLPGFA LKVEAGRVVA LLDFDSFQKI
LFKWHSNLYA ALQKCLTSSE YMHVRNAISV LRAISGVYPA VNWHGTGLQK AVDKLRDSDK
EDLKVSSQAL LGALHRREKA WVETTKFRRG PEKKGEQEQP SSQPSTTPSQ DAAPSDTKTT
TQQSNADIKD EPMPDAPPKP AATSDPEKTE SAELSRTTRL QPTAEPFIPS SRPSSRPATT
NGASTPSRQS SEASGASKRD IRPSRPEPSK PHDLPRRLTP PPPSRSTLAS LPGRPEPVDS
RNGHRDSPRL SNRADIEPAR LPPDVRTSHS RDARSGYRGS ERPERPDHGF DDYDRHSRRY
ERPEAPPYPG REDRGYGRDH ERRGPYDRPL PPQERDRPPI RAPPSERERE IREPGPRSRP
PPALEPPRSE PQAPPRKETP SEPAINPARA SLIGGAGEQR SPSTRGHGLD RPSRPSRPSS
PRRDEERKPY PRREVEERTR PETPSTRQLS ETRNNGPSLE PPSSNSRLSG PGAYRREPRE
ARQPPAIDMQ HGRLEQESSP RASQSQTPDR PQEAEVPSGP RGRPPSGGGP RMRAPPLNTQ
VPPTPPADRP TPTGPSRRQH GRSSSYAEAS PASSTPATDS AGVHPSRLSQ IDAAASESSR
PSQSVQPPQQ AHPPAGPRGN APPGAPSGPS PTSRGPPSGP QSGDSSVRGG RTNRNPLTGI
NNTLAQAGTS SARGRGGSRQ NSANFGLHMP PPPPPPPPGG PSPGLGPSPD GHAANDLFAS
SNPNDVPVGN RQPSSRHDGG RGDRRSELAE DRGSERRSSR HSSRHDESRG DREHRSERDG
RDGKDERHSA GEPPRREERP SRRENHASEG DDRRGGHARS GPRDESQSSR KHGRDEEPNA
YARGHGSGGG GGRGGDKRLR RGL
//
