ID A0A0D2G108_9EURO Unreviewed; 637 AA.
AC A0A0D2G108;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Cytochrome b5 heme-binding domain-containing protein {ECO:0000259|PROSITE:PS50255};
GN ORFNames=PV04_08036 {ECO:0000313|EMBL:KIW65814.1};
OS Phialophora macrospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW65814.1, ECO:0000313|Proteomes:UP000054266};
RN [1] {ECO:0000313|EMBL:KIW65814.1, ECO:0000313|Proteomes:UP000054266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW65814.1,
RC ECO:0000313|Proteomes:UP000054266};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; KN846960; KIW65814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2G108; -.
DR STRING; 5601.A0A0D2G108; -.
DR HOGENOM; CLU_011398_4_5_1; -.
DR OrthoDB; 1605658at2759; -.
DR Proteomes; UP000054266; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010960; Flavocytochrome_c.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01813; flavo_cyto_c; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR PANTHER; PTHR43400:SF8; HYPOTHETICAL FUMARATE REDUCTASE (EUROFUNG); 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 553..629
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT REGION 495..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69318 MW; 76616BFB6A950065 CRC64;
MAPPRVIVVG GGLSGLSAAH TVYLNGGNIL VLDKNNFFGG NSTKATSGIN GALTRTQVEL
GIQDSVKQFY EDTLKSARDK ARPDLIRVLT YQSAAAVEWL QDVFNLDLTL VSRLGGHSFP
RTHRGHDAKF PGMAITYALM QRMEELCESD PDRVQVIKKA KVTKLNKEGN VITGVTYEFG
GEEHSVDGVV ILATGGYAAD FGETSLLKKH RPDTFNLSST NGTHATGDGH KMLMAIGAND
IDMDKVQVHP TGLVDPKDPH SKWKFLAAEA LRGEGGILLN SDGQRFCDDL GHRDYVSGKM
WEEKEKGKWP IRLILNSKAS NVLDFHTRHY SGRGLMKKMT GKELAKEIGC GEAALEKQFK
EYNAIAKGDK KDPWGKKYFH NMPLEINDTF HVALMEPVLH FTMGGMEIND KAQVLNKEQK
PFDALFACGE LAGGVHGANR LGGSSLLGCV VYGRVAGNSA SKYLLEKLTT EGGASGASNR
LGQISLHIDP NSPGKISVEW GSGSGGSSGP SVGTKETTQQ AQRSAAPVMD GNKSQDPAKK
KDANDISNFK VPEKEYTLEE VAKHNKKDDL WIAVKGVVMD VTNWLDEHPG GPQALFSHMG
KDASEEFEML HDDEVIPKYA ADIVIGRVKG QEVRLEY
//
