ID A0A0D2GQL9_9EURO Unreviewed; 462 AA.
AC A0A0D2GQL9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
GN ORFNames=Z517_11494 {ECO:0000313|EMBL:KIW74724.1};
OS Fonsecaea pedrosoi CBS 271.37.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442368 {ECO:0000313|EMBL:KIW74724.1, ECO:0000313|Proteomes:UP000053029};
RN [1] {ECO:0000313|EMBL:KIW74724.1, ECO:0000313|Proteomes:UP000053029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 271.37 {ECO:0000313|EMBL:KIW74724.1,
RC ECO:0000313|Proteomes:UP000053029};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea pedrosoi CBS 271.37.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC {ECO:0000256|ARBA:ARBA00010107}.
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DR EMBL; KN846976; KIW74724.1; -; Genomic_DNA.
DR RefSeq; XP_013278532.1; XM_013423078.1.
DR AlphaFoldDB; A0A0D2GQL9; -.
DR STRING; 1442368.A0A0D2GQL9; -.
DR GeneID; 25310984; -.
DR VEuPathDB; FungiDB:Z517_11494; -.
DR HOGENOM; CLU_011815_0_1_1; -.
DR OrthoDB; 118560at2759; -.
DR Proteomes; UP000053029; Unassembled WGS sequence.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.60.60; N-acetyl transferase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002717; HAT_MYST-type.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR10615:SF180; HISTONE ACETYLTRANSFERASE SAS2; 1.
DR Pfam; PF01853; MOZ_SAS; 2.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51726; MYST_HAT; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000053029};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 31..384
FT /note="MYST-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51726"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 287
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR602717-51"
SQ SEQUENCE 462 AA; 51742 MW; 0DE416E8BF1608DC CRC64;
MPPAVVKTNN TSTSVLQDGS PHRSRRASFQ VLNRNIHQVV LGNLLFDAWY YSPYPDSIIL
PHRGDGSTTA DVRNGHSHSH LSGFHSSIRG EEPICRLLHV CPCCFRYTPL EEQFTRHLAY
HRHLRSENLE LNQPVPASAY KVYEWEGYAV WEIDGEKEKL YCQNLSLFGK LFLEQKSVFF
DTAGFKYYAL TYTKPESPPS PASTTTKTRG QKQRSSSANV QQEDDALYQT RVLGFFSKEN
LSWDSNNLAC ILIFPPFQHR QLGQLLMAVS YKLSGWEWEG GVIGGPEKPL SAMGRKSYLR
FWSERIARFL MGQTADADAT RVFDKAKANG RNRKTVQPRK EEMTVKEIGD RTGMLGEDVV
AALTEMGLCK VVGPKRKKAK SSTPEANGTA SASLAHATEI EPEELATMVI HRSKIVEWAE
KNGVELSSPV KEEGFLGEWA LSDLAESDNN SQNVSGDEDS NA
//
