ID A0A0D2H9S4_9EURO Unreviewed; 466 AA.
AC A0A0D2H9S4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein {ECO:0000259|PROSITE:PS00624};
GN ORFNames=Z520_05936 {ECO:0000313|EMBL:KIX98635.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX98635.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX98635.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX98635.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; KN848071; KIX98635.1; -; Genomic_DNA.
DR RefSeq; XP_016632758.1; XM_016776439.1.
DR AlphaFoldDB; A0A0D2H9S4; -.
DR STRING; 1442371.A0A0D2H9S4; -.
DR GeneID; 27711682; -.
DR VEuPathDB; FungiDB:Z520_05936; -.
DR OrthoDB; 2392848at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR PANTHER; PTHR11552:SF78; GMC_OXRDTASE_N DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411}.
FT DOMAIN 285..299
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 235
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 466 AA; 51162 MW; 116F629D742E4ACC CRC64;
MAQFDLDKHG AMDVIFAGGG TAACVAAGRL AKANPDLKIL LIEGGPNNFQ DPTVVHPAAY
LTHLAPESKT ALFYKAKPSK YLNGREAVVP TGGILGGGSS INFMMYTRAQ GVDFDSWNTV
GWNAREIMPL LNKLETFQQG ESAINQRRHG HEGPIHVSSG GFRSKSEHVF MDSIKAMGFK
EIVDLQDLDQ VGGFSRWQRY VSLDGKRQDA AHCYIHPRLR DGKHPNLHIL VHSKVVRVIF
DEQAVPPRAI GVEYQTDPEH QPALSLSKPT LQFIRAAKLV VVSAGALGSP QILERSGIGN
SQLLEGLKIK VISDLRGVGE NYQDHHLVLS SYTSNLPPTE TLDELFSSRK SFATAIQEKD
PRMGWNGIDI ASKLRMTDEE VKLLGADFEA DWKRDFAPHP TRPVMLCGVI NAFLGDAATV
EPGQYFTVGT YTAYPYSRGS IHINSANDTV CGYDCDETGE ARWCRG
//
