ID A0A0D2HC71_9EURO Unreviewed; 842 AA.
AC A0A0D2HC71;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=Z520_05056 {ECO:0000313|EMBL:KIX99480.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX99480.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX99480.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX99480.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; KN848069; KIX99480.1; -; Genomic_DNA.
DR RefSeq; XP_016633603.1; XM_016775560.1.
DR AlphaFoldDB; A0A0D2HC71; -.
DR STRING; 1442371.A0A0D2HC71; -.
DR GeneID; 27710802; -.
DR VEuPathDB; FungiDB:Z520_05056; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 83..728
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 389
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 842 AA; 93393 MW; AE99C1E67A1CAD81 CRC64;
MSSTGTGTRY FAHPKSLDET LNSSPRENGD LANMSKSQEE QSFEAAKETT ASYTKKEQEP
VSLKKEVSKP GITFAAQDKL PKLPIPELDS SMKKYLDALA PLQSPQEHND TKAAVRDFLE
NEGKDLQERL KKYATGRTSY IEQFWYDSYL NYDNPVVLNL NPFFLLEDDP TPARNNQVTR
AASLVISALC FVRAVRKEEL PPDTLRGTPL CMYQYSRLFG TARVPTENGC IIGQDSDSKH
VVVMCRGQFY WFDVLDDNND VIMTEKDLAI NLQVIVDDAE QTPIQEAAKG AIGVLSTENR
KVWSHLRDLL TRDEGSNNAE CLSIVDSALF MICLDYTEPT NVSQLAGNML CGTSVVERGV
QVGTCTNRWY DKLQIIVCKN GSAGINFEHT GVDGHTVLRF ASDVYTDTIL RFAKSINGQA
PTLWTSQSPD PSKRDPDSFG DVSTTPHKLE WDMIPELQIA LRFAETRLAD LINQNEFQTL
DFAGYGKNFI TSMGFSPDAF VQMAFQAAYY GLYGRVENTY EPAMTKMFFH GRTEAIRTVT
PECVEFVKTF WADNAAQKKV DALRAATQKH TAITKESSKA QGSDRHLYAL YCVWQRKVND
ESAEIGSTAG FSSNGYSSPT DVSDFGSPKR LEESSSPIGR SRTGTESSRS PAPALQQMPA
LFSDAGWDKI NNTIISTSNC GNPSLRHFGF GPTSGDGFGI GYIIKDDTIS ICASSKHRQT
QRFVDSLESY LNEIRRLLRA TKTKDAAASK ITRAREAEEK AGKDGRLKSR GRIIKTEASK
VDGFQTPTSL DTAEVEDDGL GGYGFFDAGM LLQALKKDQP KPSEQIAQRR KAVGKKLALS
EY
//
