ID A0A0D2HCC6_9EURO Unreviewed; 1618 AA.
AC A0A0D2HCC6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=Z520_05126 {ECO:0000313|EMBL:KIX99550.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX99550.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX99550.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX99550.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN848069; KIX99550.1; -; Genomic_DNA.
DR RefSeq; XP_016633673.1; XM_016775630.1.
DR STRING; 1442371.A0A0D2HCC6; -.
DR GeneID; 27710872; -.
DR VEuPathDB; FungiDB:Z520_05126; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 840..860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1014..1035
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1055..1078
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1090..1112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1118..1144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1156..1183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1203..1221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..698
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1263..1490
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1618 AA; 177820 MW; 2E44B3FEB33646BF CRC64;
MALFVRQVAT LTLKNLLAAF VRRWFSTTIR AFLLPCIFVG FLSYARFLFI PPSVYGIGDP
TPIRSLSEAL DLVSGGRDKL VFVNNGFSDG PIQLVIDKVV NDTGSFGGRI EILSQEQELL
TVCRNSIRGT SSCIAGAVFF SSPSEGEAAH WNYTIRADGG LQSKIVTDSS KNDNEIYLLP
LQHAIDRAIS EVEAGTNGAT VLPNAADEYP YTSLTKQERL NRIRTRYMGG IIDILAVAFF
IGVVGVTYQL TGVIASEREN GMAQLLDCMM PNLKRWQPQM ARIIANHLAF DILYGPGWII
MAIILCAGVF SKTSAAIVII FNILAGLSMS SFSILGGAFF KKAQLSGITS VIVSLLLAII
AQVASKAGTA SVAILSLLFP PMNYVYFTIF MARWERQDLG TNLVKRAPEN TSALPGIALW
IFLIIQILVF PILGAYVERT LYGTASQSRR TTYSDDNTSI SLSGFTKEYP PSWLARVRAL
FTRKRLTTVL AVDNLTLDAT RGQIVVLLGA NGSGKSTTLD AIAGLNSITS GEITVNFPEA
HTGLGFCPQK NVLWDDLTVE EHVRIFNRIK SRKPSSKEES LQLLASCDID RKSGARSKTL
SGGQKRKLQL AMMFTGGSRV CCVDEVSSGL DPLSRRKIWD ILLAERGSRS IVLTTHFLDE
AELLADHIAI LSKGILKASG TSVELKHKLG SGYRVHVYHT HGSQHLPTYK DVSHIRRDDQ
TIYALTDSGK AADFLRRIES EGVVEYQVNG PTIEDVFLKV AEEVKLVQQP GEKTGTNHIL
QEVGSHSSTE IDPDNAVKAM IRDESSGEPP QLLDGRRISM PKQALVLFSK RWVVLRRNTL
PYLAALLIPI IAAGLVTLFL NNFQKTTCSP ASLALVSDIE SLSSQVNYDL VAGPRDRLGQ
NAIQLFASTL AGSTGVAGIA ANTTKLLDSI HLVDTLDEFN NYIDTRFANV TPGGFFLGDS
TSPPTFAWQG DGNIAFSVII QNAMDTLLTN SSISTQYQAF DVPWGADVGK ALQLITYFGL
AMAVYPSFFA LYPTIERLRN VRGLHYSNGV RSAPLWFAYT TFDFVIVVLT SSITIIIFRA
VTDVWYHIEY LFVVFFLYGL TSTLLSYVIS LFSRSQLAAF AFASGGQAVM FLLYFIAYMS
VLTYSPIDKI DRNVNICHFT IAIISPVANL TRALFVTLNV FSITCRNREF ASYAGSMTTF
GGPILYLILQ SFLLFGLLLW WDSGPLFRHF RKKQQEEEVE ERDTVEAEVS NELTRVSSSQ
DGLRVLNLSK RFGKTLAVNN VTFGVPRSEV FALLGPNGAG KSTTISLIRG DIQPSRRGGD
ILVDNISVIR HRAQARSRLG VCPQFDAMDT MTVSEHLYFY ARVRGVSDPR HNVDAVMRAV
GLEQYAERMA AKLSGGNKRK LSLGIALMGN PSVLLLDEPS SGMDAASKRV MWRTLESVVP
GRSLVLTTHS MEEADALATR AGIMAGKMLA LGTTDYLRRK HGDAYYVHLV HGRAPHASDD
DMLRIRDWIM CSFPDANIES KVYAGQIRFS VPTKGLYASK DGEISAESGI ASLFTALEKN
KSELQIEYYS VSRATLDQVF LNIVGKHNVE EEGGETTSTA KTGFIKELSR VSTRLVHK
//
