ID A0A0D2J338_9EURO Unreviewed; 492 AA.
AC A0A0D2J338;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=choline-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00026101};
DE EC=2.7.7.15 {ECO:0000256|ARBA:ARBA00026101};
GN ORFNames=Z518_01147 {ECO:0000313|EMBL:KIX10066.1};
OS Rhinocladiella mackenziei CBS 650.93.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Rhinocladiella.
OX NCBI_TaxID=1442369 {ECO:0000313|EMBL:KIX10066.1, ECO:0000313|Proteomes:UP000053617};
RN [1] {ECO:0000313|EMBL:KIX10066.1, ECO:0000313|Proteomes:UP000053617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 650.93 {ECO:0000313|EMBL:KIX10066.1,
RC ECO:0000313|Proteomes:UP000053617};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Rhinocladiella mackenzie CBS 650.93.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR EMBL; KN847475; KIX10066.1; -; Genomic_DNA.
DR RefSeq; XP_013277202.1; XM_013421748.1.
DR AlphaFoldDB; A0A0D2J338; -.
DR STRING; 1442369.A0A0D2J338; -.
DR GeneID; 25289218; -.
DR VEuPathDB; FungiDB:Z518_01147; -.
DR HOGENOM; CLU_034585_5_1_1; -.
DR OrthoDB; 5474784at2759; -.
DR Proteomes; UP000053617; Unassembled WGS sequence.
DR GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; IEA:InterPro.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR045049; Pcy1-like.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR10739:SF13; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR10739; CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000053617}.
FT DOMAIN 159..286
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 1..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..492
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 54202 MW; C483F09193EA4191 CRC64;
MSSPSSSASA KRKRTSGPDR LKSAATDLQQ PSHDASGEEL AASLSHNTRN RKHTPSNSVD
STVPPRKRAR TRSNANSYES NGTRAPDPAQ HPGPSSHDDE AEEAEEHGKK RQRTFLGATT
KAVVNGDGGT MQDPPKAGLR EPVGYKTNPP PTGRPVRVYA DGVFDLFHLG HMRQLEQAKT
AFPDTYLIVG VTGDAETHKR KGLTVLTGAE RAETVRHCRW VDEVIPNCPW IVTPAFLAEH
KIDYVAHDDE PYGAEEGDDI YAPIKKEGKF LVTQRTEGVS TTGIITKIVR DYEKYIVRQL
KRGTSRQELN ISWLKKNELD IKRHVQELRD SIKTNWATAG GEISRDFRQF WLNASSRPAS
PAPFNRQHSD GLRSPSAVSA VEHLKHLDIP GSTDKRSDSP GRISRNEDFA TGYSLGLIGG
VKSWMMRGRR ALRDSQGPSP EGSEDDEARS PISNDGDAVG IGLKTPPMGR GRKGKSESEL
EDTRREAMDV MH
//
