ID A0A0D2JH83_9EURO Unreviewed; 316 AA.
AC A0A0D2JH83;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIX92537.1};
GN ORFNames=Z520_11713 {ECO:0000313|EMBL:KIX92537.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX92537.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX92537.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX92537.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate +
CC succinate; Xref=Rhea:RHEA:16809, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:30031, ChEBI:CHEBI:57429; EC=4.1.3.30;
CC Evidence={ECO:0000256|ARBA:ARBA00001050};
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DR EMBL; KN848103; KIX92537.1; -; Genomic_DNA.
DR RefSeq; XP_016626660.1; XM_016782201.1.
DR AlphaFoldDB; A0A0D2JH83; -.
DR STRING; 1442371.A0A0D2JH83; -.
DR GeneID; 27717459; -.
DR VEuPathDB; FungiDB:Z520_11713; -.
DR OrthoDB; 554215at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00377; ICL_PEPM; 1.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR039556; ICL/PEPM.
DR InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR42905; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR42905:SF2; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR Pfam; PF13714; PEP_mutase; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411}.
SQ SEQUENCE 316 AA; 33471 MW; 7BC33C87B63A8221 CRC64;
MAPTDEALFP KSKIQAASGG VTRLRQLLTD ESHIVVCPGV YDGFTARIAL AAGFECLYMT
GAGTTMSRLG LPDLGLATLN DMRDNASMIA GLDRDIPLIA DADTGYGGPL MVGRTVSAYI
SGGVAALHLE DQVMNKRCGH LRGKQVVEEE VFLSRIKAAV KMRAQTGRDI VVIARTDAMQ
LLGYDAAVDR LRKALAVGAD VAFLEGIRSK EEARQVCKDL YPAPVLLNMA HGGLTPSISV
AEAQEMGFRI IIFPGLAVQS VYGAVTKAVK ELRETGDIKY LEGGVPSPGE IYGVCGMQEA
VDFDLAAGAS TYTNGV
//
