ID A0A0D2JJA3_9EURO Unreviewed; 413 AA.
AC A0A0D2JJA3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=Z518_00560 {ECO:0000313|EMBL:KIX09480.1};
OS Rhinocladiella mackenziei CBS 650.93.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Rhinocladiella.
OX NCBI_TaxID=1442369 {ECO:0000313|EMBL:KIX09480.1, ECO:0000313|Proteomes:UP000053617};
RN [1] {ECO:0000313|EMBL:KIX09480.1, ECO:0000313|Proteomes:UP000053617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 650.93 {ECO:0000313|EMBL:KIX09480.1,
RC ECO:0000313|Proteomes:UP000053617};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Rhinocladiella mackenzie CBS 650.93.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847475; KIX09480.1; -; Genomic_DNA.
DR RefSeq; XP_013276616.1; XM_013421162.1.
DR AlphaFoldDB; A0A0D2JJA3; -.
DR GeneID; 25288631; -.
DR VEuPathDB; FungiDB:Z518_00560; -.
DR HOGENOM; CLU_005533_5_2_1; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000053617; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000053617};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 242..389
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 318
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 413 AA; 45970 MW; D452DCEB1C1BFC9D CRC64;
MSSPAKDEAE QLQELVQQLA AAAKDYVPSS GPQNYIDRSN ITRKAKEIMR LMMAPSDMPL
YHTVNMIEVV AIRTLRGLGV FEKIPVEGSI SLADLSKATN VQDSLLERML RLLVGVGFVD
QTADYKYGHT KFSKAYTFPV PGPGNHFQML FDENFSTMWN FHNYVKEVAG GGMPSEPDDS
QNNPYTHRHG MDGRPVWDVL ANLPDRLKAF QLGFMAQEDS GPIIGFFDYA ALFDPATDGD
RPTLVDVGGG QGQSIMQILQ ATPSLDPSRM VLQDLPEPVQ QAQESKMLPE GVRIMVHDFW
TPQPIKGAKA YFIRRIMHDY SDENCTKILR QIRDAMSPDS KVLIADMVMP KRVSEADLPA
AAMDNCMMVM GGKERTEENF SKILSNAGLK LSKVWRSREG GATGNLVEAR LMD
//
