ID A0A0D2JL59_9EURO Unreviewed; 1087 AA.
AC A0A0D2JL59;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Inositol polyphosphate-related phosphatase domain-containing protein {ECO:0000259|SMART:SM00128};
GN ORFNames=Z518_01281 {ECO:0000313|EMBL:KIX10200.1};
OS Rhinocladiella mackenziei CBS 650.93.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Rhinocladiella.
OX NCBI_TaxID=1442369 {ECO:0000313|EMBL:KIX10200.1, ECO:0000313|Proteomes:UP000053617};
RN [1] {ECO:0000313|EMBL:KIX10200.1, ECO:0000313|Proteomes:UP000053617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 650.93 {ECO:0000313|EMBL:KIX10200.1,
RC ECO:0000313|Proteomes:UP000053617};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Rhinocladiella mackenzie CBS 650.93.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847475; KIX10200.1; -; Genomic_DNA.
DR RefSeq; XP_013277336.1; XM_013421882.1.
DR AlphaFoldDB; A0A0D2JL59; -.
DR STRING; 1442369.A0A0D2JL59; -.
DR GeneID; 25289352; -.
DR VEuPathDB; FungiDB:Z518_01281; -.
DR HOGENOM; CLU_005563_0_0_1; -.
DR OrthoDB; 996872at2759; -.
DR Proteomes; UP000053617; Unassembled WGS sequence.
DR GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProt.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR048869; OCRL-1_2_ASH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF299; PHOSPHOINOSITIDE 5-PHOSPHATASE; 1.
DR Pfam; PF21310; OCRL-like_ASH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000053617}.
FT DOMAIN 67..499
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1087 AA; 121147 MW; 6CF2574150073B6B CRC64;
MSLKPKDEFD QSQLPPPSLK SSDPWATDPQ TPGAFPVSPE AQEGVVSAPH SLSAAVKARR
DEYIRKMSMR IKIGTWNVAS INGTEKDLGA WFVEGYGGRS LSQELAGTSV EDDQDSDSDE
NGESVESQEA RMSRKKTTVP MDDVPAETHG HRIDLYVLGL QEIVDVTSMT EAVKPYTDPN
PGQKWKKALK HALPVGFSKI AEQQLLGLLI LVYASPELAP SISSVSATSV GTGLMGYLGN
KGAVAVRIVV GEATKLCFVN CHLAAGADQT ALNRRTWDTN QILNRTRFPL ASLDGEAAED
GEEKIGDEDF GFWFGDLNYR LDDIPGEDVR RLLLLHTRNE YDSENISQRR IDSELGFISA
PSNEHFEHRD QERPASESTS GPELDPKSDP ASLHTTLQSL LAHDQLRTQQ RLQKAFHEGW
REGEINFLPT YKYDVGSVGM FDSGEKQRSP SWCDRILYRT RRDKEMHEEK AKQLAEARKK
DESMKARGID EATVEHDVLF DYDPETDGLA YGDDYDEYEE REENFHDAEL VQTREDDGDL
IELHSYNSHQ RVLSSDHKPL GAIFTLTYDA VIPELKAKIH QEVARELDKA ENEGRPAVTV
VVDDHSDELG PNADGAADMN AVHFGDVRYG VKKTRMVTIA NTGQIAASFS FVERPTESEE
GARVVPEWLE LHLESHVMQQ SGQAHKPGDQ ISLSPGETTS IELSIDVTDG RLVYELNKGI
TQLEDILVLR IENGRDHFIP VKGNWLQSSF FRTLDELVVA PEGGVRKLPK SHKNRDSTGT
GNVHSSATHH SAPKELYSLT EILPIFIERS IAEWGMIHDE DIPPWQYENG GLSWPFNRDT
WTFHEGEERL ELLAGVREAL DTAAPLDRNL DPDVPGIVRL EILAETLISF LQSLRDGIIS
AEIWSDVEVR LSTMEKGKAH PSPEEIQDMV MDVLSQFPVH SVSFTFITFL MNRIVNELVP
CGKPAPTSGT PAPASPNPSR RSRASTLSVD SGDTPLMSGQ ETPGKRGLFL TLRRHRTQSI
SSSSDPTTEA VMAASERRKQ LIRAYVEIFA PIITRSENDT NYKGKDKKAL EGRKRRVLEV
FLNARHV
//
