ID A0A0D2K3L5_9EURO Unreviewed; 693 AA.
AC A0A0D2K3L5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit {ECO:0000256|ARBA:ARBA00015765};
DE AltName: Full=ERF-3 {ECO:0000256|ARBA:ARBA00031881};
DE AltName: Full=ERF2 {ECO:0000256|ARBA:ARBA00030845};
DE AltName: Full=Polypeptide release factor 3 {ECO:0000256|ARBA:ARBA00029585};
DE AltName: Full=Translation release factor 3 {ECO:0000256|ARBA:ARBA00030210};
GN ORFNames=Z520_04073 {ECO:0000313|EMBL:KIY00388.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIY00388.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIY00388.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIY00388.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN848067; KIY00388.1; -; Genomic_DNA.
DR RefSeq; XP_016634510.1; XM_016774583.1.
DR AlphaFoldDB; A0A0D2K3L5; -.
DR STRING; 1442371.A0A0D2K3L5; -.
DR GeneID; 27709819; -.
DR VEuPathDB; FungiDB:Z520_04073; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03704; eRF3_C_III; 1.
DR CDD; cd04089; eRF3_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003285; Sup35.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF36; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01343; YEASTERF.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 263..486
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 75481 MW; 7F594BF64A226CBC CRC64;
MAGNFDSWED AAAQEEDLSK RTQNMNMNAN TFRPGAASFQ PGAATFQPGQ PYQQNGYQNY
GYGQQQGYNQ YPQYGQQYNQ YPQYQQQQGY NQGYNSGQFA AYNQTPGGFQ PRQGAPISIA
KRSDTQPAPA PTPQQAPAPA AKAEAIPDAP APKPQPAAAA PPKAKVLSIG VPTSASATPK
KPASPTTKDE PTPPKAEAGA KVAAAKAVEK TGEKVSGKAS PTPSSGKSSP TPADAKKQRN
ADEVAQSQTA DVDASVLEEM YGKEHVNIIF IGHVDAGKST LGGQVLIQTG MVDERTLEKY
KRDAKDAGRE TWYISWVLDL NKEERAKGKT VEVGRGFFET EKRRYTILDA PGHKTYVPNM
LSGAAQADVA ILVISARKGE FETGFEKGGQ TQEHAMLIKT TGAKELVVVV NKMDDPTVEW
SKERYDEIVG KLKPYLKKRI GLDSTFMPIS AQTGVNVRDR IDPSVADWYK GPSLLEFLDG
MAKIQRNINA PFMMPIGAKY RDMGTMIEGR VEAGVVQKSS TLIMMPNREE VGIAALYGET
EDEVPYATCG DQVRMRLRGI EEEDIQPGFV LCSPKRLVHC VSEFEAQINI VELKSILSAG
FNCVIHVHAA TEEVTFAALL HKLEPKTGRK SKKPPPFAAK GQNIIARLQV TSGGGKICVE
RFEDYPQLGR FTLRDQGQTI AVGKITKLIL DDD
//
